摘要
目的总结肝泡型棘球蚴病(hepatic alveolar echinococcosis,HAE)的外科手术治疗现状及新理念,为进一步提升外科手术根治率提供参考。方法复习近年来关于HAE治疗的研究文献并加以综述。结果HAE的生物学行为虽然类似于恶性肿瘤,但其肝内病灶往往生长缓慢,因而临床症状出现较晚。目前临床上该病的治疗以外科手术为主,其中又以根治性切除手术作为首选。药物治疗在控制疾病进展和复发上也具有重要价值。近年来随着外科技术的进步,手术方式也逐步向多模式结合的方向发展,尤其是既往无法行常规根治手术的病例。结论临床多模式结合的治疗理念能使更多HAE患者获益,乃至达到临床根治性切除,从而提升外科手术根治率。
Objective To summarize the research status and new directions of surgical treatment of hepatic alveolar echinococcosis(HAE)in clinic,and to provide reference for further research in improving the rate of radical surgery.Method The recent literatures on the studies of HAE were reviewed.Results Although the biological behavior of HAE was similar to that of malignant tumor,the clinical symptoms appeared late as the intrahepatic lesions often grow slowly.At present,the treatment of this disease was mainly surgical operation,among which radical resection was the first choice.Drug therapy was also of great value in controlling disease progression and recurrence.In recent years,with the progress of surgical technology,the surgical method had gradually developed to the direction of multi-mode combination,especially for those cases that had not been able to perform conventional radical surgery before.Conclusion The treatment concept of clinical multi-mode combination can benefit more patients,even achieve clinical radical resection,and improve the rate of radical resection.
作者
何洋
王文涛
HE Yang;WANG Wentao(Department of Liver Surgery,West China Hospital Sichuan University,Chengdu 610041,P.R.China)
出处
《中国普外基础与临床杂志》
CAS
2021年第9期1243-1248,共6页
Chinese Journal of Bases and Clinics In General Surgery
基金
四川省科技厅重点研发项目(项目编号:2019YFS0029)
国家自然科学基金项目(项目编号:81770566)
四川大学华西医院医疗新技术/新项目基金(项目编号:XJS2016004)
四川省科技计划项目(项目编号:2019YFS0529)。
关键词
肝泡型棘球蚴病
手术多模式治疗
多学科协作诊疗
自体肝移植
综述
hepatic alveolar echinococcosis
multimodal surgical treatment
multi-disciplinary treatment
autologous liver transplantation
review
