摘要
血清淀粉样蛋白A作为急性反应时相蛋白在动脉粥样硬化的形成过程中有明显的促进作用。血清淀粉样蛋白A通过刺激炎症因子的释放导致炎症的产生,与脂蛋白结合改变高密度脂蛋白的生理功能,引发血管内皮和平滑肌功能障碍,还会引起血栓形成,这些都促进动脉粥样硬化的发生发展。
Serum amyloid A has a significant effect on the formation of atherosclerosis as an acute reaction,leading to inflammation by stimulating the release of inflammation factors.It is vital for atherosclerosis that serum amyloid A combined with lipoprotein changes the physiological function of high density lipoprotein.Serum amyloid A can affect the function of vascular endothelium and smooth muscle,and also cause thrombosis,which all promote the development of atherosclerosis.
作者
夏可心
刘海霞
XIA Kexin;LIU Haixia(Department of Cardiology,the Second Affiliated Hospital of Harbin Medical University,Harbin,Heilongjiang 150001,China)
出处
《中国动脉硬化杂志》
CAS
2021年第10期913-916,共4页
Chinese Journal of Arteriosclerosis
基金
教育部“春晖计划”合作科研项目(HLJ2019026)。
