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宫颈癌根治术后患者高危型HPV载量和SCC-Ag检测结果与术后复发的相关性 被引量:6

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摘要 目的分析宫颈癌根治术后高危型人乳头瘤病毒(HPV)载量和鳞状细胞癌抗原(SCC-Ag)检测结果与术后复发的相关性。方法选取2014年11月-2019年10月嘉兴市妇幼保健院妇产科收治的宫颈癌根治术后复发患者50例为研究组,另选择宫颈癌根治术后非复发患者50例为对照组。比较两组高危型HPV载量和SCC-Ag检测结果,分析与术后复发的相关性。结果研究组高危型HPV载量和SCC-Ag检测阳性率分别为82.00%和62.00%,均明显高于对照组的38.00%和42.00%,差异均有统计学意义(χ^(2)=38.720,P=0.011;χ^(2)=27.090,P=0.017)。研究组ⅡA期比例(56.00%)显著高于对照组(22.00%),差异有统计学意义(Z=-4.547,P=0.029)。多因素Logistic回归分析显示:宫颈癌FIGO分期、高危型HPV载量及SCC-Ag是宫颈癌根治术后复发的影响因素(均P<0.05)。结论高危型HPV载量和SCC-Ag检测对宫颈癌根治术后复发有重要的临床参考价值。
作者 陈婷婷
出处 《中国妇幼保健》 CAS 2021年第18期4211-4213,共3页 Maternal and Child Health Care of China
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