摘要
百草枯是一种广泛使用的高效除草剂,会产生超氧阴离子和其他自由基,导致严重毒性反应。而百草枯中毒是危及生命的疾病,可涉及多个系统脏器,导致多器官功能衰竭,其中肺是主要靶器官。目前,发病机制尚未完全阐明,临床没有特效的治疗手段。文章就近年来非编码RNA在百草枯中毒发病机制中的研究进展作一综述。
Paraquat is a highly effective and widely used herbicide that produces superoxide anions and other free radicals,leading to severe toxicity.Paraquat poisoning is a life-threatening disease that can involve multiple organs and lead to multiple organ failure,among which lung is the main target organ.At present,there is no effective treatment and the pathogenesis has not been fully elucidated.This article reviews the recent progress in the pathogenesis of paraquat poisoning by non-coding RNA.
作者
孟婷婷(综述)
李铁刚(审校)
Meng Tingting;Li Tiegang(Emergency Department of Shengjing Hospital Affiliated to China Medical University,Shenyang 110004,China)
出处
《疑难病杂志》
CAS
2021年第10期1063-1066,共4页
Chinese Journal of Difficult and Complicated Cases
基金
国家自然科学基金面上项目(81772056)
中国医科大学附属盛京医院杰出人才基金(MF89)345人才工程(M0273)。
