摘要
目的:系统评价急性心肌梗死(AMI)再灌注治疗后斑点追踪超声心动图(STE)测得的纵向应变(LS)对于心肌梗死面积(MIS)的诊断价值。方法:检索Pubmed、Cochrane library、Embase、中国知网、维普及万方等数据库于2021年2月前发表关于STE测得的LS与以心脏磁共振延迟钆增强测得的AMI患者再灌注治疗后MIS为金标准相关性的中、英文文献。应用STATA 15.0及Meta-DiSc 1.4对纳入文献的数据进行统计学分析,采用QUADAS-2评价纳入文献质量。结果:最终纳入13篇文献,共688例心肌梗死患者,其中10篇文献涉及二维整体纵向应变(2D-GLS)与金标准合并r为0.66(95%CI:0.61~0.71),3篇文献涉及三维整体纵向应变与金标准合并r为0.36(95%CI:0.23~0.50)。3篇文献涉及2D-GLS诊断MIS≥12%患者的合并敏感度、特异度、诊断比值比、受试者工作特征曲线AUC分别为0.76(95%CI:0.62~0.87)、0.89(95%CI:0.81~0.94)、25.00(95%CI:6.53~95.62)、0.8710;5篇文献涉及节段二维纵向应变诊断透壁梗死节段的以上参数分别为0.79(95%CI:0.74~0.83)、0.80(95%CI:0.79~0.82)、14.40(95%CI:9.22~22.48)、0.8166。结论:STE测得的二维纵向应变可作为评估AMI患者再灌注治疗后MIS的良好指标。
Objective:To systematically evaluate the diagnostic value of longitudinal strain(LS)measured by speckle tracing echocardiography(STE)in diagnosing myocardial infarct size(MIS)after acute myocardial infarction(AMI)reperfusion therpy.Methods:Searching for Chinese and English literatures on the correlation between LS measured by STE and MIS in AMI patients after reperfusion therapy measured by cardiac magnetic resonance late gadolinium enhancement published before February 2021 in database such as Pubmed,Cochrane library,Embase,CNKI,VIP and Wanfang.STATA 15.0 and meta-disc 1.4 were used for statistical analysis of the data in the included literatures,QUADAS-2 was used to evaluate the quality of the included liter-ature.Results:Finally,13 articles were included,a total of 688 patients with myocardial infarction.Among them,10 literatures involved two-dimensional global longitudinal strain(2D-GLS)and gold standard combination pooled r is 0.66(95%CI:0.61-0.71),Three literatures related to three-dimensional global longitudinal strain and gold standard pooled r is 0.36(95%CI:0.23-0.50).Three literatures related to 2D-GLS in the diagnosis of MIS≥12%and the pooled sensitivity、specificity、diagnosis odds ratio、AUC of receiver operating characteristic curve were 0.76(95%CI:0.62-0.87)、0.89(95%CI:0.81-0.94)、25.00(95%CI:6.53-95.62)、0.8710,respectively.The above parameters for the diagnosis of segmental transmural infarction by the segmental two-dimensional longitudinal strain in 5 literatures were 0.79(95%CI:0.74-0.83)、0.80(95%CI:0.79-0.82)、14.40(95%CI:9.22-22.48)、0.8166,respectively.Conclusions:The two-dimensional longitu-dinal strain measured by STE could be used as a good index to evaluate MIS in AMI patients after reperfusion therapy.
作者
曾健
黄建
单凯
周军
王芋霖
李征真
ZENG Jian;HUANG Jian;SHAN Kai;ZHOU Jun;WANG Yulin;LI Zhengzhen(Department of Radiology,Jiangjin District Central Hospital of Chongqing,Chongqing 402260,China)
出处
《心肺血管病杂志》
CAS
2021年第9期970-975,共6页
Journal of Cardiovascular and Pulmonary Diseases
关键词
心肌梗死面积
纵向应变
斑点追踪超声心动图
心脏磁共振
综合分析
Myocardial infarct size
Longitudinal strain
Speckle tracking echocardiography
Cardiac magnetic resonance
Meta-analysis
