摘要
目的探讨不同剂量米非司酮在治疗子宫肌瘤当中发挥的效用。方法以2018年12月—2019年12月为研究时间范围,择取在此期间诊治的78例子宫肌瘤患者为研究对象。以奇数偶数法为例对患者分组,常规组和试验组各39例。其中,常规组患者予以高剂量米非司酮实施治疗;试验组采取小剂量米非司酮进行治疗。比较两组子宫肌瘤患者治疗后的子宫大小与子宫肌瘤大小变化情况、激素水平变化情况、用药期间不良反应发生的概率以及总治疗有效率。结果在小剂量米非司酮作用下,患者的子宫大小与子宫肌瘤大小变化情况较好于常规组;患者的激素水平更加稳定;患者的用药期间不良反应发生的概率得到了显著的降低;药物总治疗有效率更高,P<0.05。结论研究结果表明,小剂量米非司酮治疗子宫肌瘤有着明显的疗效,在保证患者用药安全性的同时有助于患者病情更好的稳定,用药价值显著。
Objective To explore the effect of different doses of mifepristone in the treatment of uterine fibroids.Methods A total of 78 patients with uterine fibroids treated in our hospital during the period from December 2018 to December 2019 were selected as the study subjects.Taking the odd and even number method as an example,the patients were divided into the normal group and the experimental group,with 39 cases each.Patients in the conventional group were treated with high dose mifepristone.The experimental group was treated with low dose mifepristone.The changes of uterine size and uterine fibroids,hormone levels,the incidence of adverse reactions and the total effective rate of treatment were compared between the two groups.Results The changes of uterine size and uterine fibroids in patients with low dose of mifepristone were better than those in the control group.The hormone levels of the patients were more stable.The incidence of adverse reactions was significantly reduced.The total effective rate was higher(P<0.05).Conclusion The research results show that low dose mifepristone has an obvious curative effect in treating uterine fibroids, which not only ensures the safety of medication, but also contributes to the better stability of patients' condition. The medication is of significant value.
作者
吴海霞
肖新益
WU Haixia;XIAO Xinyi(Department of Gynecology,Aikang Hospital,Huangshi Hubei 435000,China)
出处
《中国继续医学教育》
2021年第25期182-185,共4页
China Continuing Medical Education
关键词
米非司酮
子宫肌瘤
临床效果
子宫大小
肌瘤大小
激素水平
mifepristone
uterine fibroids
clinical effect
uterine size
fibroids size
hormone levels
