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妊娠期高血压疾病孕妇分娩前后抗心磷脂抗体的变化与疾病分期的相关性研究 被引量:1

Research on the correlation between the change of anticardiolipin antibody in pregnant women with hypertensive disorder complicating pregnancy before and after delivery and disease stagin g
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摘要 妊娠期高血压疾病(hypertensive disorders of pregnancy,HDP)是导致孕产妇和围产儿死亡的重要原因之一,是妊娠与血压升高并存的一组疾病[1],基本病理生理变化是全身小血管痉挛和血管内皮损伤。抗心磷脂抗体(antixardiolipin antibody,ACA)属于自身免疫性抗体,是抗磷脂抗体(antiphospholipid antibodies,APA)中的一类;其抗原为与阴电荷磷脂相结合的血浆蛋白。大量的研究证实,由于免疫因素的参与可造成胎盘组织和功能的改变,导致妊娠的不良结局。本研究拟探讨抗心磷脂抗体在妊娠期高血压疾病孕妇分娩前后的变化与妊娠期高血压疾病分期的关系,从而判断疾病的严重程度,现报告如下。
作者 包蕾 王爱华 孙宇 沈翠花 BAO Lei;WANG Ai-hua;SUN Yu
出处 《云南医药》 2021年第5期449-450,共2页 Medicine and Pharmacy of Yunnan
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