摘要
目的探讨季德胜蛇药联合冰片霜外敷辅助治疗蝮蛇咬伤的效果。方法选取2017年6月-2020年6月在南京中医药大学附属苏州市中医医院治疗的80例蝮蛇咬伤患者,按照随机数字表法分为双药治疗组40例,采用药物季德胜蛇药和冰片霜共同治疗;单药治疗组40例,用季德胜蛇药治疗。统计两组治疗前及治疗后一周生命体征及血清学变化、疼痛积分、肿胀程度、疼痛和肿胀消失时间以及治疗效果。结果治疗后双药治疗组的痊愈比例、显效比例、总有效率(37.5%、32.5%、97.5%)均大于单药治疗组比例(30.0%、25.0%、87.5%)(P<0.05)。治疗后两组的疼痛积分、肢体周经比治疗前降低(P<0.05),且双药治疗组低于单药治疗组(P<0.05)。双药治疗组的疼痛、肿胀消失时间均短于单药治疗组(P<0.05)。治疗后两组的呼吸、心率、C反应蛋白(C-reactive protein,CRP)、肌酸激酶同工酶(creatine kinase-MB,CK-MB)、乳酸脱氢酶(lactate dehydrogenase,LDH)均比治疗前降低(P<0.05),且双药治疗组低于单药治疗组(P<0.05)。结论双药治疗组总有效率显著高于单药治疗组,能有效降低疼痛积分、肿胀高度,缩短疼痛、肿胀消失时间,降低血清学指标水平以及呼吸、心率,治疗蝮蛇咬伤效果显著。
To investigate the efficacy of Jidesheng snake medicine combined with borneol frost externally in the treatment of agkistrodon bite.Methods A total of 80 viper bite patients treated in our hospital from June 2017 to June 2020 were selected and divided into a two-drug treatment group according to the random number table method.40 patients were treated with jidessheng snake medicine and borneol cream.In the monotherapy group,40 cases were treated with Jidesheng snake medicine.The vital signs and serological changes,pain score,swelling degree,time to disappear of pain and swelling and treatment effect of the two groups were counted.Results The recovery rate,the obvious effect rate and the total effective rate(37.5%,32.5%and 97.5%)in the double-drug treatment group were all higher than that in the single-drug treatment group(30.0%,25.0%and 87.5%)(P<0.05).After treatment,the pain score and peripheral meridian of the patients in the both groups were lower than those before treatment(P<0.05),and the double-drug treatment group was lower than the single-drug treatment group(P<0.05).The pain and swelling time of the patients in the two-drug treatment group was lower than that in the single-drug treatment group(P<0.05).After treatment,respiration,pulse,C-reactive protein(CRP),creatine kinase isoenzyme(CK-MB)and Lactate dehydrogenase(LDH)in the both groups were all lower than those before treatment(P<0.05),and the double-drug treatment group was lower than that in the single-drug treatment group(P<0.05).Conclusion The total effective rate of the two-drug treatment group was significantly higher than that of the single-drug treatment group,which could effectively reduce the pain score and swelling height of the injured,shorten the pain and swelling disappearance time of the injured,reduce the level of serological indicators,respiration and pulse,and have a significant effect on the treatment of agkistrodon viper bite.
作者
许贤君
欧阳礼平
庞晓娜
XU Xianjun;OUYANG Liping;PANG Xiaona(The Emergency Critical care Medi-cine Department of Suzhou Hospital of Traditional Chinese Medicine affiliated to Nanjing University of Chinese Medi-cine,Suzhou Jiangsu 215009,China)
出处
《中国急救复苏与灾害医学杂志》
2021年第10期1175-1177,1201,共4页
China Journal of Emergency Resuscitation and Disaster Medicine
关键词
季德胜蛇药
冰片霜
蝮蛇咬伤
Jidesheng snake medicine
Borneol cream
Viper bites
