摘要
目的探讨血府逐瘀汤与胺碘酮联合治疗急性心肌梗死(AMI)并心律失常的效果及对红细胞免疫功能的影响。方法选择2019年5月—2020年4月该院收治的AMI并心律失常患者90例,以随机数字表法将其分为两组。对照组45例应用胺碘酮注射液治疗,研究组45例在此基础上联合血府逐瘀汤治疗。对比两组患者的治疗效果,治疗前后的红细胞免疫功能指标红细胞免疫复合物花环率(RICR)与红细胞C3b受体花环率(RBC-c3bRR),以及不良反应情况。结果在总有效率对比中,研究组为93.33%较对照组的75.56%更高,差异有统计学意义(χ^(2)=5.414,P<0.05)。治疗后,研究组RICR水平(5.3±0.7)%较对照组(6.6±0.5)%更低,差异有统计学意义(t=10.138,P<0.001),RBC-C3bRR水平(17.6±1.0)%较对照组(15.0±1.8)%更高,差异有统计学意义(t=8.470,P<0.001)。两组治疗期间均未见严重不良反应。结论血府逐瘀汤与胺碘酮联合治疗AMI并心律失常疗效确切,且有效改善了红细胞免疫功能,安全可靠,适于临床应用。
Objective To investigate the effect of Xuefu Zhuyu Decoction and amiodarone in the treatment of acute myocardial infarction(AMI)with arrhythmia and its influence on red blood cell immune function.Methods From May 2019 to April 2020,90 patients with AMI and arrhythmia were selected and divided into two groups by random number table.45 cases in the control group were treated with amiodarone injection,and 45 cases in the study group were treated with Xuefu Zhuyu Decoction on this basis.The treatment effect of the two groups of patients was compared,the red blood cell immune function index red blood cell immune complex rosette rate(RICR)and red blood cell C3b receptor rosette rate(RBC-c3bRR)before and after treatment,as well as adverse reactions.Results In the total effective rate comparison,93.33%of the study group was higher than 75.56%of the control group,the difference was statistically significant(χ^(2)=5.414,P<0.05).After treatment,the RICR level of the study group(5.3±0.7)%was lower than that of the control group(6.6±0.5)%,the difference was statistically significant(t=10.138,P<0.001),and the RBC-C3bRR level(17.6±1.0)%was higher than that of the control group(15.0±1.8)%,the difference was statistically significant(t=8.470,P<0.001).There were no serious adverse reactions during the treatment period in the two groups.Conclusion The combination of Xuefu Zhuyu Decoction and amiodarone in the treatment of AMI with arrhythmia has a definite effect,and it can effectively improve the immune function of red blood cells.It is safe and reliable and suitable for clinical application.
作者
吕芳芳
焦健
LYU Fangfang;JIAO Jian(Department of Critical Care Medicine,Jinan Hospital of Traditional Chinese Medicine,Jinan,Shandong Province,250012 China;Emergency Department,Jinan Hospital of Traditional Chinese Medicine,Jinan,Shandong Province,250012 China)
出处
《世界复合医学》
2021年第8期73-75,共3页
World Journal of Complex Medicine
关键词
血府逐瘀汤
胺碘酮
急性心肌梗死
心律失常
红细胞免疫功能
Xuefu zhuyu decoction
Amiodarone
Acute myocardial infarction
Arrhythmia
Red blood cell immune function
