摘要
目的:探讨PET/CT对偶然发现的结直肠局灶性^(18)F-FDG摄取增高灶的诊断价值。方法:回顾分析30例共30个PET/CT偶发的结直肠局灶性^(18)F-FDG摄取增高灶的影像特征、内镜及病理资料。根据病理结果,将病变分为恶性组,良性组。分析两组SUVmax、浓聚灶形态、浓聚最大径及CT上肠壁厚度有无差异。结果:30例共30个偶发性^(18)F-FDG浓聚灶中24例共24个浓聚灶肠镜检查发现异常且位置符合PET/CT描述,阳性预测值为80%(24/30)。良性组17例共17个,占56.67%(17/30)。恶性组13例共13个,占43.33%(13/30)。良性组与恶性组平均SUVmax、团状浓聚灶占比、浓聚最大径及CT上肠壁厚度分别为7.45±5.59、58.82%(10/17)、(1.99±0.57)cm及(0.89±0.59)cm和9.32±4.03、92.31%(12/13)、(2.91±1.18)cm及(1.46±0.69)cm。2组病变SUVmax及浓聚灶形态均无统计学意义(P均>0.05),浓聚最大径及肠壁厚度差异均有统计学意义(P均<0.05)。结论:PET/CT对于无明确肠道病史患者的结直肠偶发局灶性^(18)F-FDG摄取增高灶具有较高的阳性预测值,尽管良恶性病变的SUVmax无显著差异,但恶性病变的^(18)F-FDG浓聚范围及肠壁的厚度均明显高于良性病变。
Objective:To evaluate the diaognosis value of PET/CT in incidental focal ^(18)F-FDG uptake of colorectum.Methods:Retrospective analysis of PET/CT imaging features,endoscopy and pathological data of 30 patients with 30 foci of incidental focal colorectal ^(18)F-FDG uptake.According to the pathological results,patients were divided into malignant group and benign group.The differences between the two groups in SUVmax,the form and maximum diameter of the ^(18)F-FDG concentrated foci,and the thickness of the intestinal wall on CT were analyzed.Results:Among 30 cases with 30 incidental 18FFDG concentration foci,24 foci were found and the location were consistent with PET/CT description,with a positive predictive value of 80%(24/30).There were 17 foci in benign group accounting for 56.67%(17/30);13 foci in malignant group accounting for 43.33%(13/30).The mean SUVmax,the proportion of massive foci,diameter of concentration foci and intestinal wall thickness in the benign group and the malignant group were 7.45±5.59,58.82%(10/17),(1.99±0.57)cm,(0.89±0.59)cm and 9.32±4.03,92.31%(12/13),(2.91±1.18)cm and(1.46±0.69)cm,respectively.There was no statistically significant difference in SUVmax and the form of ^(18)F-FDG concentrated foci between the two groups(all P>0.05),and the difference in the maximum diameter of concentrated foci and intestinal wall thickness was statistically significant(all P<0.05).Conclusion:PET/CT showed a higher positive predictive value for increased colorectal incidental focal ^(18)F-FDG uptake in patients without a clear intestinal history.Although there was no significant difference in SUVmax value between benign and malignant lesions,the 18FFDG concentration range and intestinal wall thickness of malignant lesions were significantly higher than that of benign lesions.
作者
祝安惠
贾红敏
张卫方
ZHU An-hui;JIA Hong-min;ZHANG Wei-fang(Department of Nuclear Medicine,Peking University Third Hospital,Beijing 100191,China;Department of Imaging,the Central Hospital of Aerospace,Beijing 100049,China)
出处
《中国临床医学影像杂志》
CAS
CSCD
2021年第10期733-737,共5页
Journal of China Clinic Medical Imaging
基金
2016年国家科技部数字化诊疗装备研究试点专项(2016YFC0104005)。
