摘要
目的探讨盐酸氨溴索治疗老年肺炎的疗效及安全性。方法64例老年肺炎患者,采用随机摸球法分为对照组及观察组,各32例。对照组给予常规治疗,观察组在对照组的基础上给予盐酸氨溴索治疗。比较两组患者的症状改善时间,治疗前后的咳痰量与咳嗽程度评分,治疗效果,不良反应发生情况。结果观察组患者的体温恢复时间、咳嗽消失时间、肺部哮鸣音消失时间分别为(2.30±0.56)、(3.23±0.53)、(3.01±0.97)d,均短于对照组的(4.61±0.85)、(6.02±0.93)、(7.53±0.62)d,差异具有统计学意义(P<0.05)。治疗后,观察组患者的咳痰量、咳嗽程度评分均低于对照组,差异具有统计学意义(P<0.05)。观察组患者的治疗总有效率96.9%高于对照组的71.9%,差异具有统计学意义(P<0.05)。观察组患者的不良反应发生率3.1%低于对照组的28.1%,差异具有统计学意义(P<0.05)。结论老年肺炎患者采用盐酸氨溴索治疗,可加快患者的症状恢复速度,减少咳痰量,减轻咳嗽程度,提高治疗效果,减少不良反应,安全性较高。
Objective To discuss the efficacy and safety of ambroxol hydrochloride in the treatment of senile pneumonia.Methods A total of 64 senile patients with pneumonia were divided into control group and observation group according to random ball-touching method,with 32 cases in each group.The control group received conventional treatment,and the observation group received ambroxol hydrochloride for treatment.The time of symptom improvement,sputum production and cough degree scores before and after treatment,treatment effect,and occurrence of adverse reactions were compared between the two groups.Results In the observation group,the recovery time of body temperature,the disappearance time of cough and the disappearance time of wheezing sound were(2.30±0.56),(3.23±0.53)and(3.01±0.97)d,respectively,which were shorter than(4.61±0.85),(6.02±0.93)and(7.53±0.62)d in the control group,and the differences were statistically significant(P<0.05).After treatment,patients in the observation group had lower sputum production and cough degree scores than those of the control group,and the difference was statistically significant(P<0.05).The total effective rate of treatment in the observation group was 96.9%,which was higher than 71.9%in the control group,and the difference was statistically significant(P<0.05).The incidence of adverse reactions in the observation group was 3.1%,which was lower than 28.1%in the control group,and the difference was statistically significant(P<0.05).Conclusion Ambroxol hydrochloride for senile patients with pneumonia can speed up the recovery of symptoms,reduce sputum production,reduce the degree of cough,improve the therapeutic effect and reduce adverse reactions with higher safety.
作者
陈小庆
CHEN Xiao-qing(Department of Pharmacy,Jinzhou Second Hospital,Jinzhou 121000,China)
出处
《中国现代药物应用》
2021年第19期8-10,共3页
Chinese Journal of Modern Drug Application
关键词
盐酸氨溴索
老年肺炎
不良反应
治疗效果
Ambroxol hydrochloride
Senile pneumonia
Adverse reaction
Therapeutic effect
