摘要
目的探讨丁苯酞联合阿托伐他汀对脑梗死患者美国卫生院卒中量表(NHISS)评分的影响。方法选取2016年5月至2019年5月于本院接受治疗的脑梗死患者70例,按照随机数字表法分为观察组和对照组,每组35例。在常规治疗基础上,对照组采用阿托伐他汀治疗,观察组采用在对照组基础上联合丁苯酞治疗。比较两组治疗前后NHISS频分、Barthel指数量表评分与不良反应(胃肠反应、头晕、头痛)发生率。结果治疗后,两组NIHSS评分降低,Barthel评分升高,且观察组NIHSS评分低于对照组,Barthel评分高于对照组,差异有统计学意义(P<0.05);两组不良反应发生率比较差异无统计学意义。结论丁苯酞联合阿托伐他汀对脑梗死患者的疗效确切,能有效改善患者的神经功能与日常活动能力,且用药安全性高。
Objective To observe the influence of butyphthalide combined with atorvastatin on the scores of the National Institutes of Health Stroke Scale(NHISS)in patients with cerebral infarction.Methods A total of 70 patients with cerebral infarction who treated in the hospital from May 2016 to May 2019 were selected as subjects,and they were divided into observation group and control group according to random number table,with 35 cases in each group.Based on routine treatment,control group was treated with atorvastatin,and observation group was combined with butyphthalide treatment on basis of the control group.The NIHSS scores,Barthel index before and after treatment,and the incidence of adverse reactions(gastrointestinal reaction,dizziness,headache)during treatment were compared between two groups.Results After treatment,the scores of NIHSS in two groups decreased,the score of Barthel index increased,the score of NIHSS in observation group was lower than that in control group,and the score of Barthel index in observation group was higher than that in control group(P<0.05);the incidence of adverse reactions between two groups was not statistically significant.Conclusion Butyphthalide combined with atorvastatin in treatment of patients with cerebral infarction has definite effects,it can improve nerve function and activity of daily living of patients,which has high medication safety.
作者
李卫青
LI Weiqing(Department of Neurology,Dexing People's Hospital,Shangrao,Jiangxi,334200,China)
出处
《当代医学》
2021年第31期38-40,共3页
Contemporary Medicine
关键词
脑梗死
阿托伐他汀
丁苯酞
Cerebral infarction
Atorvastatin
Butyphthalide
