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肺腺癌化疗患者生活质量与癌因性疲乏的相关性 被引量:3

Correlation Between Quality of Life and Cancer-Related Fatigue in Patients with Lung Adenocarcinoma Chemotherapy
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摘要 目的探讨肺腺癌化疗患者生活质量与癌因性疲乏的关系。方法以2017年1月至2018年12月于商丘市第一人民医院接受化疗的60例肺腺癌患者为研究对象。在化疗最后1个疗程结束前采用癌症患者生命质量测定量表(FACT-G)评估其生活质量,采用Piper疲乏量表中文版(RPFS-C)评估其癌因性疲乏程度,分析生活质量与癌因性疲乏程度的关系。结果60例患者FACT-G总分为(61.20±13.87)分。经RPFS-C量表评估,癌因性疲乏轻度18例,中度28例,重度14例。轻度癌因性疲乏患者FACT-G评分低于中度、重度患者(P<0.05),中度癌因性疲乏患者FACT-G评分低于重度患者(P<0.05)。有配偶患者FACT-G评分低于无配偶患者(P<0.05)。Pearson相关分析显示,RPFS-C评分与FACT-G评分呈正相关(r=0.587,P<0.05)。结论肺腺癌化疗患者生活质量与癌因性疲乏程度密切相关,改善患者癌因性疲乏,有助于提高患者生活质量。 Objective To investigate the relationship between the quality of life and cancer-related fatigue in patients with lung adenocarcinoma chemotherapy.Methods Sixty patients with lung adenocarcinoma who received chemotherapy at the First People’s Hospital of Shangqiu from January 2017 to December 2018 were the subjects of this study.Before the end of the last course of chemotherapy,functional assessment of cancer therapy-general(FACT-G)scale was used to assess their quality of life,and the Chinese version revised Piper fatigue scale(RPFS-C)was used to assess the degree of cancer-related fatigue.The relationship between the quality of life and the degree of cancer-related fatigue was analyzed.Results The total FACT-G score of 60 patients was(61.20±13.87).According to the RPFS-C scale,there were 18 cases of mild cancer-related fatigue,28 cases of moderate cancer-related fatigue,and 14 cases of severe cancer-related fatigue.The FACT-G score of patients with mild cancer-related fatigue was lower than that of patients with moderate and severe cancer-related fatigue(P<0.05).The FACT-G score of patients with moderate cancer-related fatigue was lower than that of patients with severe cancer-related fatigue(P<0.05).The FACT-G score of patients with spouse was lower than that of patients without spouse(P<0.05).Pearson correlation analysis showed that RPFS-C score was positively correlated with FACT-G score(r=0.587,P<0.05).Conclusion The quality of life of patients undergoing chemotherapy for lung adenocarcinoma is closely related to the degree of cancer-related fatigue.The relief of cancer-related fatigue could help improve the quality of life of patients.
作者 邬晓琨 WU Xiaokun(Department of Cardiology,Shangqiu First People’s Hospital,Shangqiu 476100,China)
出处 《河南医学研究》 CAS 2021年第31期5838-5841,共4页 Henan Medical Research
关键词 肺腺癌 化疗 生活质量 癌因性疲乏 相关性 lung adenocarcinoma chemotherapy quality of life cancer-related fatigue correlation
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