摘要
目的:探讨腹腔镜胃切除术(LG)联合D2淋巴结清扫治疗进展期胃癌的临床疗效及安全性。方法:纳入2012年6月至2016年6月收治的行根治性远端胃切除术的224例胃癌患者。其中108例行LG,116行开腹胃切除术(OG)。对比分析两组患者围手术期相关指标、手术并发症、无进展生存率及总生存率。结果:LG组手术时间长于OG组[(244.9±39.9)min vs.(205.1±42.5)min,P<0.001],差异有统计学意义;LG组术中出血量、术后下床时间、术后通气时间、住院时间均少于OG组,差异有统计学意义(P<0.001);两组术后并发症发生率差异无统计学意义(P>0.05)。两组不同临床病理分期患者术后5年无进展生存曲线、5年总生存曲线差异均无统计学意义(P>0.05)。结论:LG治疗进展期胃癌的术后短期疗效优于OG,长期生存情况与OG相似,不会增加肿瘤复发与转移的风险。
Objective:To evaluate the short-term and long-term clinical efficacy and safety of laparoscopic gastrectomy(LG)combined with D2 lymph node dissection for advanced gastric cancer.Methods:From Jun.2012 to Jun.2016,224 patients with gastric cancer who underwent radical distal gastrectomy were included.Among them,108 patients were treated with LG and 116 patients were treated with open gastrectomy(OG).Firstly,the perioperative indicators and surgical complications of the two groups were compared and analyzed.Secondly,patients in the two groups were followed up for 5 years after surgery,and the progression-free survival rate and overall survival rate of the two groups were compared and analyzed.Results:The operation time of LG group was significantly longer than that of OG group[(244.9±39.9)min vs.(205.1±42.5)min,P<0.001],the intraoperative blood loss,postoperative ambulation time,postoperative ventilation time and hospital stay in LG group were less than those in OG group(P<0.001),the differences were statistically significant.There was no significant difference in the incidence of postoperative complications between the two groups(P>0.05).There were no statistically significant differences in 5-year progression-free survival curve and 5-year overall survival curve between two groups of patients with different clinicopathological stages(P>0.05).Conclusions:The short-term efficacy of LG is better than that of OG in the treatment of advanced gastric cancer,and the long-term survival efficacy is similar to OG,and LG dose not increase the risk of tumor recurrence and metastasis.
作者
张建荣
陈斌
曾欢
詹发杰
ZHANG Jian-rong;CHEN Bin;ZENG Huan(Department of Gastrointestinal Surgery,Wuwei People's Hospital,Wuwei 733000,China)
出处
《腹腔镜外科杂志》
2021年第10期763-767,共5页
Journal of Laparoscopic Surgery
基金
武威市科学技术局科技计划项目(WW160221)。
关键词
胃肿瘤
胃切除术
腹腔镜检查
剖腹术
Stomach neoplasms
Gastrectomy
Laparoscopy
Laparotomy
