摘要
目的分析云南省大理州妊娠期妇女良性甲状腺疾病患病情况,为该地区妊娠期甲状腺疾病的防治提供科学依据。方法2014年7-12月,将云南省大理州按东、西、南、北、中划分为5个抽样片区,每个片区抽取1个乡(镇),每个乡(镇)抽取妊娠早、中、晚期妇女至少20例。通过病史采集、甲状腺超声检查及甲状腺功能血清学指标检测,以本地区妊娠期特异的甲状腺功能血清学指标正常参考值为标准,进行妊娠期甲状腺疾病患病情况调查。结果共调查妊娠期妇女370例,其中妊娠早期120例(城镇61例、农村59例),年龄为19~40岁;妊娠中期126例(城镇60例、农村66例),年龄为19~45岁;妊娠晚期124例(城镇57例、农村67例),年龄为19~44岁。妊娠期妇女甲状腺疾病检出率为27.57%(102/370),其中甲状腺功能异常检出率为7.57%(28/370),甲状腺抗体阳性检出率为11.62%(43/370),甲状腺结节检出率为13.51%(50/370)。其中妊娠早、中、晚期甲状腺疾病检出率分别为33.33%(40/120)、23.02%(29/126)、26.61%(33/124),比较差异无统计学意义(χ^(2)=3.362,P>0.05)。结论云南省大理州妊娠期妇女甲状腺疾病特别是妊娠早期甲状腺疾病检出率有较高趋势,有必要进一步开展更大规模的调查研究,为该类疾病的防治提供更可靠的科学依据。
Objective To investigate and analyze the prevalence of thyroid disease during pregnancy in Dali,Yunnan Province,and to provide scientific basis for prevention and treatment of benign thyroid disease during pregnancy in the region.Methods From July to December 2014,Dali in Yunnan Province was divided into 5 sampling areas according to east,west,south,north and middle.One township(town)was selected from each area,and at least 20 women in early,middle and late pregnancy,respectively,were selected from each township(town).To conduct this investigation,medical history data was collected,thyroid ultrasound examination and serological indexes of thyroid function test were performed based on the normal reference value of specific thyroid function serological indexes during pregnancy in this region.Results A total of 370 cases of pregnant women were investigated,including 120 cases in early pregnancy(61 cases in urban areas and 59 cases in rural areas),aged 19-40 years;126 cases in middle pregnancy(60 cases in urban areas and 66 cases in rural areas),aged 19-45 years;and 124 cases in late pregnancy(57 cases in urban areas and 67 cases in rural areas),aged 19-44 years.The detection rate of thyroid disease in pregnant women was 27.57%(102/370).The detection rate of thyroid dysfunction was 7.57%(28/370),the positive detection rate of thyroid antibody was 11.62%(43/370),and the detection rate of thyroid nodule was 13.51%(50/370).The detection rates of thyroid diseases in early,middle and late pregnancy were 33.33%(40/120),23.02%(29/126),26.61%(33/124),respectively,and the difference was not statistically significant(χ^(2)=3.362,P>0.05).Conclusions In Daliy,Yunnan Province,there is a high detection rate of thyroid diseases during pregnancy,especially in early pregnancy.Therefore,it is necessary to carry out further large-scale investigation and study to provide a more reliable scientific basis for prevention and treatment of thyroid disease during pregnancy in this region.
作者
张永燕
汤建林
胡红永
罗青琴
Zhang Yongyan;Tang Jianlin;Hu Hongyong;Luo Qingqin(Department of Nuclear Medicine,the Third Affiliated Hospital of Dali University,Dali Bai Autonomous Prefecture People's Hospital,Dali 671000,China)
出处
《中华地方病学杂志》
CAS
北大核心
2021年第10期826-829,共4页
Chinese Journal of Endemiology
关键词
妊娠期
甲状腺疾病
检出率
Pregnancy
Thyroid disease
Detection rate
