摘要
以间苯二甲腈、乙醇胺为原料,无水醋酸锌或氯化锌为催化剂,合成了1,3-双(2-噁唑啉基)苯,优化了工艺条件。优化条件为:n(间苯二甲腈)∶n(乙醇胺)∶n(催化剂)=1.00∶4.00∶0.04,反应5 h,温度120~125℃。优化条件下,产品含量99.2%,反应收率94.7%,产品结构经核磁、红外和质谱确证。该工艺还提出了乙醇胺的回收方法,具有收率高、成本低、三废排放少等优势,宜于工业化生产。
2,2'-(1,3-Phenylene)bis-(2-oxazoline)was prepared from 1,3-dicyanobenzene and ethanolamine using Zn(OAc)2 or ZnCl2 as catalyst.Process conditions were optimized and obtained as followings:the ratio of n(1,3-Dicyanobenzene)∶n(ethanolamine)∶n(catalyst)was of 1.00∶4.00∶0.04;reacting time was of 5 h;the reaction temperature was at a range from 120℃to 125℃.The yield and purity of the product were reached up to 94.7%and 99.2%,respectively.The objective product was confirmed by 1 H NMR,13C NMR,IR and MS.The recovery of ethanolamine was also presented.This process has the advantages including high yield,low cost,less waste water and facile industrialization.
作者
张浩
曾桂钰
陶锡祺
ZHANG Hao;ZENG Gui-yu;TAO Xi-qi(Jiangxi Univate New Material Co.,Ltd.,Ji'an 343000,China)
出处
《精细化工中间体》
CAS
2021年第5期78-80,共3页
Fine Chemical Intermediates
关键词
噁唑啉
间苯二甲腈
乙醇胺
oxazoline
1,3-dicyanobenzene
ethanolamine
