摘要
目的:总结银屑病患者的中医体质分布规律,为银屑病的防治提供循证证据。方法:计算机检索中国知网、万方、维普、CBM、PubMed等数据库,中文主题词或关键词为"银屑病"或含"寻常型银屑病"并且"中医体质"或含"体质类型";英文主题词为Chinese medicine、constitution、Psoriasis。运用Stata SE 12.0软件对纳入研究进行单样本率的Meta分析及亚组分析。结果:纳入15篇文献,共4 609例患者,银屑病患者中主要的4种体质类型为平和质、阴虚质、气虚质、气郁质。阴虚质发生银屑病的风险比率为0.18[95%CI(0.13,0.22),P<0.000 1];气虚质发生银屑病的风险比率为0.18[95%CI(0.10,0.25),P<0.000 1];平和质发生银屑病的风险比率为0.17[95%CI(0.13,0.22),P<0.000 1];气郁质发生银屑病的风险比率为0.16[95%CI(0.11,0.21),P<0.000 1]。结论:气虚质、阴虚质及气郁质是银屑病患者的主要体质类型,气虚、阴虚及气郁可能是诱发其发病的危险因素,但此结论仍需高质量、大样本的研究以进一步验证。
Objective:To summarize the distribution law of TCM constitution in patients with psoriasis and provide TCM guidance and more advanced evidence-based evidence for the prevention and treatment of psoriasis.Methods:The databases of CNKI,Wanfang,VIP,CBM and PubMed,etc.were searched by computer.The Chinese subject words or keywords were"psoriasis"or"psoriasis vulgaris"and"TCM constitution"or"constitution type".The English subject words included Chinese medicine,constitution and psoriasis.A Meta-analysis and a subgroup analysis of single sample rate were carried out by Using Stata Se 12.0 software.Results:A total of 15 literature was included,involving 4609 patients.The main four constitution types of psoriasis patients were as follows:mild constitution,yin deficiency constitution,qi deficiency constitution,and qi stagnation constitution.The risk ratio of psoriasis in yin deficiency constitution was 0.18[95%CI(0.13,0.22),P<0.0001].The risk ratio of psoriasis in qi deficiency constitution was 0.18[95%CI(0.10,0.25),P<0.0001].The risk ratio of psoriasis in mild constitution was 0.17[95%CI(0.13,0.22),P<0.0001].The risk ratio of psoriasis in qi stagnation constitution was 0.16[95%CI(0.11,0.21),P<0.0001].Conclusion:Qi deficiency constitution,yin deficiency constitution and qi stagnation constitution are the main physical types of patients with psoriasis.Qi deficiency,yin deficiency and qi stagnation may be the risk factors inducing its onset,but this conclusion still needs high-quality and large sample research to further verify.
作者
邹佳华
龚丽萍
黄港
胡初向
晏娟
章菲燕
ZOU Jia-hua;GONG Li-ping;HUANG Gang;HU Chu-xiang;YAN Juan;ZHANG Fei-yan(Jiangxi University of Chinese Medicine,Nanchang,Jiangxi,China,330004;The Affiliated Hospital of Jiangxi University of Chinese Medicine,Nanchang,Jiangxi,China,330006)
出处
《河南中医》
2021年第12期1863-1867,共5页
Henan Traditional Chinese Medicine
基金
国家重点研发计划项目(2018YFC1705303)
江西省自然科学基金项目(20171BAB205084)
江西省2020年度研究生创新专项基金项目(YC-2020-S397)
2020年度江西中医药大学校级研究生创新专项基金项目(JZYC20S23)
江西省中医药科技计划项目(2020A0048)
江西省卫生计生委中医药科研课题项目(2018A048)。
关键词
银屑病
META分析
中医体质
平和质
阴虚质
气虚质
气郁质
psoriasis
Meta analysis
TCM constitution
mild constitution
yin deficiency constitution
qi deficiency constitution
qi stagnation constitution
