摘要
布鲁杆菌性脊柱炎(brucellosis spondylitis)是布鲁杆菌病的一种,占布鲁杆菌病发生率的2%~53%。近年来我国因养殖业的发展和城市宠物饲养的增加,布鲁杆菌性脊柱炎有流行的趋势。目前,对布鲁杆菌性脊柱炎的病变特点认识不足,治疗不规范。因此,就布鲁杆菌性脊柱炎的诊断规范、鉴别诊断、治疗规范等问题,结合诊疗的经验及近年来的相关研究进行总结,为临床工作中对布鲁杆菌性脊柱炎的诊断和治疗提供指导。布鲁杆菌性脊柱炎规范的临床诊断还依赖于流行病学史、临床表现、影像学表现和实验室检查进行综合诊断。仅从疾病的某个方面进行诊断,容易产生误诊或漏诊。尽管布鲁杆菌性脊柱炎有一些较为特殊的临床特征,但在临床中有时需与脊柱结核和脊柱肿瘤进行鉴别诊断,尤其需要与脊柱结核进行鉴别。药物治疗是治疗布鲁杆菌性脊柱炎的最基本环节或最主要环节,手术治疗是布鲁杆菌性脊柱炎的重要治疗手段。国内关于布鲁杆菌性脊柱炎的临床研究缺乏高质量的研究,对布鲁杆菌性脊柱炎的研究多为临床经验总结,缺乏随机对照研究,故进行布鲁杆菌性脊柱炎的多中心研究,对于布鲁杆菌性脊柱炎的规范治疗有重要的作用。
Brucellosis spondylitis(BS)is a kind of brucellosis,accounting for 2%to 53%of the incidence of brucellosis.In recent years,the disease is prevalent in China because of the development of aquaculture and the increase of urban pet raising.At present,the pathological characteristics of BS are not well understood and the treatment is not standardized.Therefore,this paper mainly summarized the diagnosis,differential diagnosis and treatment of BS,combined with the author's experience and relevant studies in recent years,so as to provide guidance for the diagnosis and treatment of BS in clinical work.The current BS standard clinical diagnosis also relies on epidemiological history,clinical manifestations,imaging manifestations and laboratory examination for comprehensive diagnosis.Only diagnose from a certain aspect of the disease might lead to misdiagnosis or missed diagnosis,easy to misdiagnosis or missed diagnosis.Although BS has some specific clinical features,it is sometimes clinically required to be differentiated from spinal tuberculosis and spinal tumor,especially from spinal tuberculosis.Drug therapy is the most basic or important part of BS treatment,while surgical treatment is an important means of BS treatment.At present,there is a lack of high-quality clinical researches on BS in China,and most of the researches on BS are clinical experience summary,lacking randomized controlled trial research.Therefore,the multi-center study of BS plays an important role in the standardized treatment of BS.
作者
丁惠强
袁海峰
Ding Huiqiang;Yuan Haifeng(Department of Spine Surgery,General Hospital of Ningxia Medical University,Yinchuan 750000,China)
出处
《中华骨科杂志》
CAS
CSCD
北大核心
2021年第20期1443-1446,共4页
Chinese Journal of Orthopaedics
基金
宁夏回族自治区重点研发计划(2018BEG03028)。
