摘要
目的分析自身免疫性脑炎患者外周血免疫指标水平。方法本次纳入对象为我院2017年1月至2021年1月收治的自身免疫性脑炎患者30例作为研究对象,设为观察组;选取同期处于脑血管病恢复期的患者30例,设为对照组,检测与比较两组外周血免疫指标水平。结果观察组免疫治疗前后IgG、CD4、CD8、CD20及CD138比较差异均有统计学意义(P<0.05);观察组治疗前IgA、IgG、CD4、CD20及CD138与对照组比较差异均有统计学意义(P<0.05)。结论在自身免疫性脑炎致病过程中细胞免疫与体液免疫均有所参与,而经免疫治疗后免疫指标改善。
Objective To analyze the index level of peripheral blood immunity in patients with autoimmune encephalitis.Methods The subjects were 30 patients with autoimmune encephalitis from January 2017 to January 2021.30 patients in the recovery period were selected as control groups,and the peripheral blood immunization indexes were tested and compared.Results There were statistically significant differences in IgG,CD4,CD8,CD20 and CD138 in the observation group before and after immunotherapy(P<0.05);the differences in IgA,IgG,CD4,CD20 and CD138 in the observation group before treatment were statistically significant compared with the control group(P<0.05).Conclusion Both cellular and somatic immunity were involved in autoimmune encephalitis,while the immune index improved after immunotherapy.
作者
陈捷
陈名峰
CHEN Jie;CHEN Ming-feng(Department of Neurology,Fujian Provincial Jinshan Hospital,Fuzhou 350000,Fujian Province,China)
出处
《罕少疾病杂志》
2021年第6期15-16,共2页
Journal of Rare and Uncommon Diseases
关键词
自身免疫性脑炎
外周血免疫指标
体液免疫
细胞免疫
Autoimmune Encephalitis
Peripheral Blood Immune Indicators
Humoral Immunity
Cellular Immunity
