摘要
目的分析慢性乙型肝炎后肝硬化患者血清中HBV-DNA病毒载量表达水平与肝纤维化肝纤四项关系。方法选取2014年1月至2016年12月在我院接受治疗的60例慢性乙型肝炎患者作为研究对象,按照HBV-DNA病毒载量的高低将患者分为高病毒载量组、低病毒载量组,对两组纤维化主要指标肝纤四项检测结果状况、肝纤四项与HBV-DNA病毒载量关系情况进行分析和比较。结果高病毒载量中的HA、LN、PⅢP、CⅣ指标均明显高于低病毒载量组,差异有统计学意义(P<0.05);高病毒载量组和低病毒载量组患者的四项检查值均在正常范围,差异有统计学意义(P<0.05);HBV-DNA病毒载量水平与血清肝纤维化主要指标肝纤四项之间有相关性(P<0.05)。结论抗感染治疗对降低患者体内病毒含量具有促进作用,能抑制疾病发展。
Objective To analyze the relationship between the expression level of HBV-DNA viral load in serum and liver fiber in patients with chronic posthepatitis b cirrhosis.Methods A total of 60 patients with chronic hepatitis B who were treated in our hospital from January 2014 to December 2016 were selected as the research objects,according to the patients with HBV-DNA viral load of high and low will divided into high viral load,low viral load group,main indexes of two groups of fibrosis of liver fiber testing results of the four conditions,liver fiber four relations with HBV-DNA viral load condition into the analysis and comparison.Results The HA,LN,PⅢP and CⅣindexes in the high viral load group were significantly higher than those in the low viral load group,and the difference was statistically significant(P<0.05);four items in the high viral load group and the low viral load group the examination values were all within the normal range,and the difference was statistically significant(P<0.05);there was a correlation between the HBV-DNA viral load level and the four main indicators of serum liver fibrosis,liver fibrosis(P<0.05).Conclusion Anti-infective therapy can promote the reduction of the virus content in the patient's body and can inhibit the development of the disease.
作者
李剧
许琳婧
韩亚男
LI Ju;XU Linjing;HAN Yanan(Dalian Public Health Clinical Center,Dalian Sixth People's Hospital,Dalian 116031,China)
出处
《中国医药指南》
2021年第31期119-120,125,共3页
Guide of China Medicine
