摘要
目的综述肌萎缩侧索硬化症(amyotrophic lateral sclerosis,ALS)的病理机制及治疗研究进展。方法检索中国知网、万方、PubMed等数据库,检索字段主要包括ALS、病理机制、药物治疗、针刺治疗等。结果ALS病理机制复杂多样,彼此之间相互作用。目前治疗ALS药物屈指可数,针刺在治疗ALS领域已取得一定成果。结论积极探索ALS的病理机制并了解其之间相互作用为发现更多ALS治疗靶点提供理论依据。
Objective To review the pathological mechanism and treatment of ALS.Methods The databases of CNKI,Wanfang and PubMed were searched.The search fields mainly included ALS,pathological mechanism,drug treatment,acupuncture treatment,etc.Results The pathological mechanisms of ALS were complex and diverse,and they interacted with each other.At present,there are few drugs to treat ALS,and acupuncture has made some achievements in the field of treating ALS.Conclusion Actively explore the pathological mechanism of ALS and understand its interaction,so as to provide a theoretical basis for finding more therapeutic targets of ALS.
作者
郭婕
亢恺雯
李华
白呦呦
路小伟
李智智
王强
GUO Jie;KANG Kaiwen;LI Hua;BAI Youyou;LU Xiaowei;LI Zhizhi;WANG Qiang(The Second Clinical Medical School of Shaanxi University of Traditional Chinese Medicine,Shaanxi Xianyang 712046,China;School of Acupuncture and Massage,Shaanxi University of Traditional Chinese Medicine,Shaanxi Xianyang 712046,China;Shaanxi Key Laboratory of Acupuncture and Medicine,Shaanxi Xianyang 712046,China;Xianyang Key Laboratory of Neurobiology(Acupuncture),Shaanxi Xianyang 712046,China)
出处
《现代中医药》
CAS
2021年第6期6-10,共5页
Modern Chinese Medicine
基金
国家自然科学基金项目(82074555)
陕西省自然科学基础研究计划(2020JM-594)
陕西中医药大学经脉-脏腑相关研究创新团队(YL-09)。
关键词
肌萎缩侧索硬化症
病理机制
药物治疗
针刺治疗
干细胞移植
Amyotrophic lateral sclerosis
Pathological mechanism
Medication
Acupuncture treatment
Stem cell transplantation
