摘要
目的探讨采用盐酸氨溴索不同给药方式对小儿肺炎患儿进行治疗后获得临床效果以及可行性。方法方便选取该院2019年11月—2021年2月收治的88例小儿肺炎患儿作为研究对象,按照数字奇偶法分组。雾化组(44例):采用盐酸氨溴索药物进行雾化吸入治疗;口服组(44例):采用盐酸氨溴索药物进行口服治疗,就组间肺炎治疗总有效率、总不良反应(食欲减退、恶心呕吐)发生率以及症状病程展开对比。结果雾化组小儿肺炎患儿治疗总有效率97.73%高于口服组79.55%明显,差异有统计学意义(χ^(2)=7.220,P<0.05)。雾化组44例患儿完成盐酸氨溴索药物治疗后,患儿未表现出食欲减退,1例患儿表现出恶心呕吐;口服组44例患儿完成盐酸氨溴索药物治疗后,1例患儿表现出食欲减退,2例患儿表现出恶心呕吐;雾化组小儿肺炎患儿总不良反应发生率2.27%同口服组6.82%比较,差异无统计学意义(χ^(2)=0.262,P>0.05);雾化组小儿肺炎患儿咳喘病程(5.03±0.15)d、肺部啰音病程(3.83±0.23)d、高热病程(2.05±0.62)d均短于口服组小儿肺炎患儿咳喘病程(7.05±0.19)d、肺部啰音病程(6.09±0.55)d、高热病程(3.11±0.75)d明显,差异有统计学意义(t=55.351、25.146、7.225,P<0.05)。结论盐酸氨溴索药物雾化吸入治疗,同口服药物治疗比较,可使小儿肺炎患儿治疗效果获得明显增强,并且将系列症状病程显著缩短,不会导致食欲减退、恶心呕吐等不良反应增加,最终实现小儿肺炎病情快速康复。
Objective To investigate the clinical effect and feasibility of ambroxol hydrochloride in children with pneumonia after different administration methods.Methods 88 cases of pediatric pneumonia patients admitted to the hospital from November 2019 to February 2021 were conveniently selected as the research objects and were grouped according to the digital parity method.nebulization group(44 cases):ambroxol hydrochloride drug was used for nebulization inhalation treatment;oral administration Group(44 cases):Ambroxol hydrochloride was used for oral treatment,the total effective rate of pneumonia treatment,the incidence of total adverse reactions(loss of appetite,nausea and vomiting)and the course of symptoms were compared between the groups.Results The total effective rate(97.73%)of children with pneumonia in the nebulization group was significantly higher than that of the oral group(79.55%),and the difference was statistically significant(χ^(2)=7.220,P<0.05);44 children in the nebulization group completed ambroxol hydrochloride after drug treatment,the child did not show loss of appetite,and 1 child showed nausea and vomiting.After 44 children in the oral group completed the ambroxol hydrochloride drug treatment,1 child showed loss of appetite and 2 children showed nausea and vomiting,there was no significant difference in the total adverse reaction rate of children with pneumonia in the nebulization group 2.27% and the oral group 6.82%(χ^(2)=0.262,P>0.05);the course of cough and asthma in children with pneumonia in the nebulization group(5.03±0.15)d,pulmonary rales(3.83±0.23)d,and high fever(2.05±0.62)d were shorter than the oral group of children with pneumonia,cough and asthma(7.05±0.19)d,lung rales(6.09±0.55)d,the course of high fever(3.11±0.75)d was significant,and the difference was statistically significant(t=55.351,25.146,7.225,P<0.05).Conclusion Ambroxol hydrochloride drug atomization inhalation therapy,compared with oral drug therapy,can significantly enhance the therapeutic effect of children with pneumonia,and the course of the series of symptoms is significantly shortened,and it will not lead to increased appetite,nausea and vomiting and other adverse reactions,and ultimately achieve rapid recovery of children's pneumonia.
作者
孙文慧
SUN Wenhui(Department of Pediatrics,Jinan Children's Hospital,Jinan,Shandong Province,250000 China)
出处
《中外医疗》
2021年第27期84-87,共4页
China & Foreign Medical Treatment
关键词
小儿肺炎
盐酸氨溴索
雾化吸入
口服
治疗效果
不良反应
症状病程
Pediatric pneumonia
Ambroxol hydrochloride
Atomization inhalation
Oral
Therapeutic effect
Adverse reactions
Duration of symptoms
