摘要
目的分析红细胞分布宽度(RDW)和血小板计数(PLT)比值(RPR)在汉族人群不同病因脑梗死患者中的差异性。方法选取本院2020年1月至2021年1月收治的197例脑梗死患者,参照类肝素药物Org10172治疗急性缺血性脑卒中试验(TOAST)分型标准,将其分别纳入大动脉粥样硬化血栓形成性脑梗死组(AT组)、小动脉病变性脑梗死组(SAD组)、其他组,检测三组患者急性期、恢复期的RDW、PLT,并计算RPR,分析上述指标在汉族人群不同病因脑梗死患者中的差异性。结果脑梗死急性期,AT组RDW、RPR高于SAD组与其他组,SAD组PLT高于AT组与其他组,其他组RPR高于SAD组,差异有统计学意义(P<0.05)。脑梗死恢复期,AT组RDW、RPR均高于SAD组与其他组,SAD组PLT高于AT组与其他组,其他组RPR高于SAD组,差异有统计学意义(P<0.05)。结论无论是脑梗死急性期还是恢复期,AT组患者RDW、RPR均较高,而SAD组患者则以PLT升高、RPR下降为主要表现,应根据患者病因开展个体化治疗,以调控RPR比值、改善其预后。
Objective To analyze the differences in the ratio of red blood cell distribution width to platelet count(RPR)in patients with cerebral infarction of different etiologies in the Han population.Methods According to the classification criteria of the Trial of Org 10172 in Acute Stroke Treatment(TOAST),197 patients with cerebral infarction admitted to our hospital from January 2020 to January 2021 were selected.They were divided into the Atherosclerotic Thrombotic Cerebral Infarction group(AT group),the Small artery lesion cerebral infarction group(SAD group),and another group.The RDW and PLT of the three groups were tested in the acute and recovery phase,and RPR was calculated.The differences of the above indicators among patients with cerebral infarction of different etiologies in the Han population were analyzed.Results In the acute phase of cerebral infarction,the RDW and RPR of the AT group were higher than those of the SAD group and another group.The PLT of the SAD group was higher than that of the AT group and another group.The RPR of another group was higher than that of the SAD group.The difference was statistically significant(P<0.05).In the recovery period of cerebral infarction,the RDW and RPR of the AT group were higher than those of the SAD group and another group.The PLT of the SAD group was higher than that of the AT group and another group.The RPR of another group was higher than that of the SAD group,the difference was statistically significant(P<0.05).Conclusion RDW and RPR are higher in AT group patients in the acute and recovery phases of cerebral infarction,while increased PLT and decreased RPR are the main manifestations in SAD group patients.
作者
葛利娜
黄向东
GE Li′na;HUANG Xiangdong(Department of Neurology,Wenzhou Central Hospital in Zhejiang Province,Wenzhou 325000,China)
出处
《中国现代医生》
2021年第27期37-40,共4页
China Modern Doctor
基金
浙江省医药卫生科技计划项目(2020RC033)。
关键词
红细胞分布宽度
血小板计数
汉族
脑梗死
Red blood cell distribution width
Platelet count
Han nationality
Cerebral infarction
