摘要
目的探讨经鼻高流量湿化氧疗(HFNC)对呼吸衰竭患者血气指标、肺功能及全身炎症反应的影响。方法以我院2015年1月至2020年6月收治的40例呼吸衰竭患者作为研究对象,按治疗方式将其分为对照组和观察组,各20例。对照组行传统氧疗,观察组行HFNC,比较两组的血气指标、肺功能、全身炎症反应及生存质量。结果治疗后,观察组的血气指标(PaO2、PaCO2、SaO2、HCO3-)、肺功能(PEF、FVC、MVV、DLco)、全身炎症反应指标(CRP、PCT、IL-6、IFN-γ)水平及APACHEⅡ、GQOLI-74评分均优于对照组(P<0.05)。结论HFNC治疗呼吸衰竭可有效改善患者的血气指标、肺功能,减轻全身炎症反应,缓解症状,提高生存质量。
Objective To observe the effects of high-flow nasal cannula oxygen therapy(HFNC)on blood gas indexes,lung function and systemic inflammatory response in patients with respiratory failure.Methods A total of 40 patients with respiratory failure admitted in our hospital from January 2015 to June 2020 were selected as the research objects and divided into control group and observation group according to treatment methods,with 20 cases in each group.The control group received traditional oxygen therapy,and the observation group received HFNC.The blood gas indexes,lung function,systemic inflammatory response and quality of life of the two groups were compared.Results After treatment,blood gas indexes(PaO2,PaCO2,SaO2,HCO3-),lung function indexes(PEF,FVC,MVV,DLco),systemic inflammatory response indexes(CRP,PCT,IL-6,IFN-γ)levels,APACHEⅡand GQOLI-74 scores in the observation group were better than those in the control group(P<0.05).Conclusion HFNC in the treatment of respiratory failure can effectively ameliorate blood gas indexes and lung function,reduce systemic inflammatory response,alleviate symptoms and improve the quality of life.
作者
常涛
闫芳
CHANG Tao;YAN Fang(Emergency Department,the Third Hospital of Yulin,Yulin 719000,China)
出处
《临床医学研究与实践》
2021年第33期61-63,共3页
Clinical Research and Practice
关键词
呼吸衰竭
经鼻高流量湿化氧疗
血气指标
肺功能
respiratory failure
high-flow nasal cannula oxygen therapy
blood gas index
lung function
