摘要
目的分析清宁丸对前列腺癌术后患者促排便效果。方法选取在医院2017年1月—2020年1月行腹腔镜前列腺癌根治术后72 h未解大便者45例,采用随机数字法分为两组。对照组术后给予常规治疗,观察组在常规治疗基础上给予清宁丸治疗,分析两组患者治疗后的临床疗效。结果观察组治疗后12 h内排气患者17(68.00%)例,12~24 h排气患者8(32.00%)例;24 h内排便患者16例(64.00%),24~72 h排便患者9例(36.00%)。观察组整体促排便情况优于对照组(P<0.05)。两组治疗前腹胀、腹痛评分及血管内皮生长因子(VEGF)、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)水平组间比较,差异无统计学意义(P>0.05)。观察组治疗后腹胀、腹痛评分及VEGF、IL-6、TNF-α水平低于对照组(P<0.05)。观察组并发症率为12.00%(3/25),对照组为20.00%(4/20),观察组患者并发症率与对照组组间比较,差异无统计学意义(P>0.05)。结论清宁丸可减轻列腺癌术后患者腹胀、腹痛症状,调节VEGF、IL-6、TNF-α的表达水平,促进患者快速排便。
Objective To analyze the effect of Qingning Pill(清宁丸)on promoting defecation of patients with prostate cancer after operation.s Methods From January 2017 to January 2020,45 patients with unsolved stool after laparoscopic radical prostatec-tomy were randomly divided into two groups.The patients in the control group were treated with routine therapy and those in the observation group were treated with Qingning Pill on the basis of routine treatment.The clinical effects of the two groups were an-alyzed.s Results In the observation group,there were 17 patients(68.00%)with exhaust within 12 hours,8 patients(32.00%)with exhaust within 24 hours,16 patients(64.00%)with defecation within 24 hours,and 9 patients(36.00%)with defecation within 24 hours.The overall defecation promotion in the observation group was better than that in the control group(P<0.05).There was no significant difference in abdominal distension,abdominal pain score,levels of VEGF,IL-6 or TNF-αbetween the two groups before treatment(P>0.05).After treatment,the scores of abdominal distension,abdominal pain and the levels of VEGF,IL-6 and TNF-αin the observation group were lower than those in the control group(P<0.05).The complicated rate was 12.00%(3/25)in the observation group and 20.00%(4/20)in the control group.There was no significant difference be-tween the observation group and the control group(P>0.05).n Conclusion Qingning Pill can relieve abdominal distension and pain,regulate VEGF,IL-6 and TNF-α.It can promote the patients to defecate quickly.
作者
秦淑英
郑雪
付小慧
QIN Shuying;ZHENG Xue;FU Xiaohui(Anyang Vocational And Technical College,Anyang 455000,Henan,China;Anyang District Hospital,Anyang 455000,Henan,China)
出处
《中华中医药学刊》
CAS
北大核心
2021年第10期119-121,共3页
Chinese Archives of Traditional Chinese Medicine
基金
国家中医临床研究基地业务建设第二批科研专项(JDZX2017598)
河南省大中专毕业生就业创业项目(JYB2018297)。
关键词
清宁丸
前列腺癌
排便
排气
Qingning Pill(清宁丸)
prostate cancer
defecation
exhaust
