摘要
抗菌药物相关急性肾损伤(acute kidney injury,AKI)是指使用抗菌药物后,新出现的肾脏损伤或原有肾脏疾病加重。随着新型抗菌药物的日益增多和临床广泛应用,抗菌药物相关AKI有增多趋势,且后果严重,需引起高度重视。本文就抗菌药物相关急性肾损伤的流行病学、发病机制、危险因素、临床表现以及诊治进展进行综述,以期为临床治疗提供新思路。
Antibiotic-induced acute kidney injury(AKI)refers to new kidney damage or aggravation of existing kidney disease after the use of antibacterial drugs.With the continuous increase of new antibacterial drugs and their wide clinical application,antibiotic-induced AKI has an increasing trend and serious consequences,which should be paid great attention to.This review focuses on the progress of epidemiology,pathogenesis,risk factors,clinical manifestations,diagnosis and treatment of antibiotic-induced AKI,in order to provide new ideas for clinical diagnosis and treatment.
作者
张倩楠
李军辉
汪年松
ZHANG Qiannan;LI Junhui;WANG Niansong(Department of Nephrology,Tongji University Affiliated Putuo People’s Hospital,Shanghai 200060,China;Department of Nephrology,Shanghai JiaoTong University Affiliated Sixth People’s Hospital,Shanghai 200233,China)
出处
《世界临床药物》
2021年第10期833-837,共5页
World Clinical Drug
基金
上海交通大学医工(理)交叉基金(YG2019QNB14)。
关键词
抗菌药物
急性肾损伤
进展
antimicrobical agent
acute kidney injury
progress
