摘要
猪繁殖与呼吸综合征病毒(PRRSV)自20世纪80年代出现以来就不断发生变异与演化,给全球养猪业带来了不可估量的经济损失。该病毒具有两种基因型,其中基因1型PRRSV(PRRSV 1)首次暴发于德国,主要流行于欧洲地区,根据ORF5序列可分为四个亚型。虽然我国鲜有PRRSV 1感染病例的报道,但对其的防控工作不容忽视。笔者回顾性分析了PRRSV的起源及PRRSV 1的遗传演化与致病性,以期为PRRSV 1的分子流行病学研究及其免疫防控提供参考依据。
Porcine reproductive and respiratory syndrome virus(PRRSV) has been mutating and evolving continuously since its emergence in the 1980 s, which has brought inestimable economic losses to the global swine industry. There were two genotypes, PRRSV genotype 1(PRRSV 1) emerged in Germany firstly was mainly prevalent in Europe, which was clustered to four subtypes based on the ORF5 sequence. Although few cases of PRRSV 1 have been reported in China, the prevention and control of PRRSV should not be ignored. The origin of PRRSV, genetic evolution and pathogenicity of PRRSV 1 retrospectively analyzed in order to provide valuable evidences for molecular epidemiology and immune prevention and control of PRRSV 1.
作者
徐孝宙
张振东
邢军
连雪
史宏静
张守栋
XU Xiaozhou;ZHANG Zhendong;XING Jun;LIAN Xue;SHI Hongjing;ZHANG Shoudong(Jiangsu Vocational College of Agriculture and Forestry,Zhenjiang 212400,China;College of Biotechnology,Jiangsu University of Science and Technology,Zhenjiang 212018,China;CHANGJIA AGRICULTURE Co.,Ltd.,Shanghai 201600,China)
出处
《黑龙江畜牧兽医》
CAS
北大核心
2021年第21期44-47,共4页
Heilongjiang Animal Science And veterinary Medicine
基金
江苏省自然科学基金青年基金项目(BK20201005)
江苏农林职业技术学院校企合作项目(2020kj021)。
