摘要
目的:观察调Q激光辅助氨甲环酸治疗黄褐斑患者的效果。方法:回顾性分析2017年1月至2020年10月该院收治的70例黄褐斑患者的临床资料,按照治疗方法不同分为对照组和观察组各35例。对照组采用氨甲环酸治疗,观察组在对照组基础上采用调Q激光辅助治疗,比较两组临床疗效、治疗前后黄褐斑面积及严重程度(MASI)评分、皮肤病生活质量指数(DLQI)和不良反应/并发症发生率。结果:观察组治疗总有效率为94.29%(33/35),高于对照组的68.57%(24/35),差异有统计学意义(P<0.05);治疗后,观察组MASI评分和DLQI均低于对照组,差异有统计学意义(P<0.05);两组不良反应/并发症发生率比较,差异无统计学意义(P>0.05)。结论:调Q激光辅助氨甲环酸治疗黄褐斑患者可提高治疗总有效率,降低MASI评分和DLQI,效果优于单纯氨甲环酸治疗。
Objective:To observe effects of Q-switched laser-assisted Tranexamic acid in treatment of patients with melasma.Methods:A retrospective analysis of the clinical data of 70 patients with melasma in this hospital from January 2017 to October 2020 was performed.According to different treatment methods,they were divided into control group and observation group,each with 35 cases.The control group was treated with Tranexamic acid,while the observation group was treated with Q-switched laser on the basis of that of the control group.The clinical efficacy,the melasma area and severity index(MASI)score,the dermatological quality of life index(DLQI)and the incidence of adverse reactions/complications before and after the treatment were compared between the two groups.Results:The effective rate of treatment in the observation group was 94.29%(33/35),which was higher than 68.57%(24/35)in the control group,and the difference was statistically significant(P<0.05).After the treatment,the MASI score and the DLQI of the observation group were lower than those of the control group,and the differences were statistically significant(P<0.05).However,there was no statistically significant difference in the incidence of adverse reactions/complications between the two groups(P>0.05).Conclusions:Q-switched laser-assisted Tranexamic acid in the treatment of the patients with melasma can increase the effective rate of treatment and reduce the MASI score and DLQI.Moreover,it is superior to single Tranexamic acid treatment.
作者
郑辽楠
ZHENG Liaonan(Department of Dermatology of Zhecheng People’s Hospital,Zhecheng 476200 Henan,China)
出处
《中国民康医学》
2021年第21期59-61,共3页
Medical Journal of Chinese People’s Health
关键词
黄褐斑
氨甲环酸
调Q激光
生命质量
不良反应
Melasma
Tranexamic acid
Q-switched laser
Quality of life
Adverse reaction
