摘要
目的通过对75岁以上女性冠心病患者的调查,构建经皮冠状动脉介入(PCI)术后衰弱的风险预测模型,以期为高龄老年冠心病患者的临床管理提供一定的参考依据。方法使用方便抽样法,选择2019年1月至2020年12月间在西安交通大学第一附属医院心内科住院行PCI术的406例75岁以上女性冠心病患者为研究对象。使用一般资料调查表、临床衰弱量表、冠心病自我管理行为量表、心理痛苦温度计和微型营养评定简表等收集有关数据,并进行统计分析。结果75岁以上女性冠心病患者PCI术后衰弱发生率为68.2%(277/406)。手术时长(OR=2.583,P<0.01)、心理痛苦(OR=2.117,P<0.01)、日常锻炼频率(OR=0.556,P<0.05)、睡眠状况(OR=0.493,P<0.05)和共患慢性病数量(OR=1.508,P<0.05)均是其PCI术后衰弱发生的独立预测因素。ROC曲线下面积为0.781,约登指数为0.480,灵敏度为78.2%,特异度为69.8%。结论75岁以上女性冠心病患者PCI术后衰弱发生率较高,应在术前预测其衰弱发生的风险,并及时采取针对性干预措施,降低其衰弱发生风险,改善其预后,提高生活质量。
Objective Based on the investigation of female coronary heart disease patients over 75 years old,a risk prediction model on frailty after percutaneous coronary intervention(PCI)was constructed in order to provide some reference and basis for clinical management of elderly patients with coronary heart disease.Methods By convenience sampling,406 female coronary heart disease patients over 75 years old,who were admitted to the Department of Cardiology,the First Affiliated Hospital of Xi′an Jiaotong University and received PCI between January 2019 and December 2020,were recruited as the study subjects.The general information questionnaire,Clinical Frailty Scale,Coronary Heart Disease Self-Management Behavior Scale,Psychological Pain Thermometer and Mini Nutrition Assessment Scale were used to collect related data and statistical analysis was conducted.Results The incidence of frailty after PCI in female coronary heart disease patients over 75 years old was 68.2%(277/406).Duration of operation(OR=2.583,P<0.01),psychological pain(OR=2.117,P<0.01),frequency of daily exercise(OR=0.556,P<0.01),sleep status(OR=0.493,P<0.05)and number of co-morbidity(OR=1.508,P<0.05)were independent predictors of frailty after PCI.The area under the ROC curve was 0.781,with the Youden index of 0.480,the sensitivity of 78.2%and the specificity of 69.8%.Conclusion The incidence of frailty after PCI in female coronary heart disease patients over 75 years old was high.Medical workers should predict the risk of frailty before operation,take timely targeted intervention measures to reduce the risk of frailty,improve prognosis and quality of life.
作者
李娟利
王小芹
肖懿慧
李小妹
LI Juanli;WANG Xiaoqin;XIAO Yihui;LI Xiaomei(Department of Cardiology,The First Affiliated Hospital of Xi′an Jiaotong University,Shaanxi Xi'an 710061,China;Department of Geriatric Cardiovascular,The First Affiliated Hospital of Xi′an Jiaotong University,Shaanxi Xi'an 710061,China;School of Nursing,Xi′an Jiaotong University,Shaanxi Xi'an 710061,China)
出处
《中国妇幼健康研究》
2021年第10期1469-1475,共7页
Chinese Journal of Woman and Child Health Research
基金
国家自然科学基金青年资助项目(编号:82000414)
中华医学会优化抗栓科研基金资助项目(编号:BJUHFCSOARF201901-03)。
关键词
75岁以上
女性
冠心病
经皮冠状动脉介入术后衰弱
预测模型
over 75 years old
female
coronary heart disease
frailty after percutaneous coronary intervention
prediction model
