摘要
目的研究妊娠期合并人类免疫缺陷病毒(HIV)感染产妇不同分娩方式的分娩并发症及结局。方法选取广西壮族自治区柳州市妇幼保健院2018年1月至2020年1月收治的106例妊娠期合并HIV感染产妇,根据不同分娩方式分为观察组(剖宫产,50例)和对照组(阴道分娩,56例)。比较两组产前及产后12 h应激因子[血浆去甲肾上腺素(NE)、血清皮质醇(Cor)、血管紧张素Ⅱ(AngⅡ)]水平;比较两组产程时间、分娩并发症、不良妊娠结局;比较两组新生儿分娩后1、3、5 min Apgar评分及出生体重。结果产后12 h,两组NE、Cor、AngⅡ水平高于产前,且观察组高于对照组,差异均有统计学意义(P<0.05)。观察组总分娩时间短于对照组,差异有统计学意义(P<0.05)。观察组分娩并发症总发生率高于对照组,差异有统计学意义(P<0.05)。观察组不良妊娠结局总发生率低于对照组,差异有统计学意义(P<0.05)。分娩后3、5 min,两组Apgar评分低于分娩后1 min;分娩后5 min,两组Apgar评分低于分娩后3 min,差异有统计学意义(P<0.05)。分娩后1、3、5 min,两组Apgar评分比较,差异无统计学意义(P>0.05)。结论阴道分娩可降低妊娠期合并HIV感染产妇应激反应及分娩并发症,但剖宫产能缩短分娩时间,减少新生儿HIV感染风险。
Objective To study the delivery complications and outcomes of different delivery modes of pregnant women with human immunodeficiency virus(HIV)infection.Methods A total of 106 pregnant women with HIV infection admitted to Liuzhou Maternity and Child Health Care Hospital,Guangxi Zhuang Autonomous Region from January 2018 to January 2020 were selected.According to different delivery modes,they were divided into observation group(caesarean section,50 cases)and control group(vaginal delivery,56 cases).The levels of stress factors(plasma norepinephrine[NE],serum cortisol[Cor],and angiotensinⅡ[AngⅡ])were compared between two groups at 12 h after delivery and before delivery;the duration of labor,delivery complications and adverse pregnancy outcomes were compared between two groups;Apgar score at 1,3 min,and 5 min after delivery and birth weight were compared between two groups.Results At 12 h postpartum,the levels of NE,Cor,and AngⅡin two groups were higher than those before delivery,and observation group was higher than control group,and the differences were statistically significant(P<0.05).The total delivery time in observation group was shorter than that in control group,and the difference was statistically significant(P<0.05).The total incidence of delivery complications in observation group was higher than that in control group,and the difference was statistically significant(P<0.05).The total incidence of adverse pregnancy outcomes in observation group was lower than that in control group,and the different was statistically significant(P<0.05).Apgar scores of 3 and 5 min after delivery in two groups were lower than those of 1 min after delivery;Apgar scores of 5 min after delivery in two groups were lower than those of 3 min after delivery,and the differences were statistically significant(P<0.05).Apgar scores of 1,3 min,and 5 min after delivery showed no significant difference between two groups(P>0.05).Conclusion Vaginal delivery can reduce the stress response and delivery complications of pregnant women with HIV infection,but the cesarean section can shorten the delivery time and reduce the risk of neonatal HIV infection.
作者
吴蔚
石越
吴宇碧
WU Wei;SHI Yue;WU Yubi(Department of Obstetrics,Liuzhou Maternity and Child Health Care Hospital,Guangxi Zhuang Autonomous Region,Liuzhou,545001,China)
出处
《中国医药导报》
CAS
2021年第32期100-103,116,共5页
China Medical Herald
基金
广西壮族自治区卫生健康委员会自筹经费科研项目(Z20200706)。
关键词
妊娠期
人类免疫缺陷病毒
分娩方式
分娩并发症
妊娠结局
Gestational period
Human immunodeficiency virus
Delivery mode
Delivery complications
Pregnancy outcome
