摘要
作为一种永久性植入医疗材料和药物配方成分,聚乙烯醇(PVA)具有广阔的应用前景。文中仅以水为介质,通过冻融循环法成功制备了具有荧光性能的PVA、羧甲基纤维素(CMC)、羧甲基纤维素/稀土复合物(CMC/Eu,即CE)三者复合的荧光水凝胶,并采用SEM、FT-IR对水凝胶进行了形貌和结构表征。结果表明,CE、CMC和PVA间发生了氢键及其他作用,形成多孔洞结构。DSC和XRD结果表明,添加CMC后,水凝胶保持了PVA的结晶结构,但结晶度减小。水凝胶力学性能的提高得益于CE、CMC中的羟基和PVA中的羟基通过氢键以及分子链间的其他作用,改善了分子链间的融合性,提高了水凝胶各组分间的结合强度,尤其是当CMC与PVA质量比为1:5时,其拉伸弹性模量可达39.86 kPa,压缩弹性模量可达273.31 kPa。荧光光谱结果显示,当激发波长为394 nm时,PVA/CMC/CE水凝胶在635 nm附近出现Eu^(3+)的^(5)D_(0)→^(7)F_(2)特征发射峰,在紫外灯照射下显示红色荧光,表明该水凝胶在荧光探针、防伪、生物标记等方面具有潜在应用基础。
As a permanent implantable medical material and pharmaceutical formulation component,Polyvinyl alcohol(PVA)has a wide range of applications.In this work,water was used as the only medium to successfully prepare a composite fluorescent hydrogel of PVA,carboxymethyl cellulose(CMC)and carboxymethyl cellulose/rare earth complex(CMC/Eu,i.e.CE)by a freeze-thaw cycle method.The morphology and structure of the hydrogels were characterized by SEM and FT-IR.The results show that hydrogen bonding and other interactions occurred among CE,CMC and PVA to form multi-pore structure.DSC and XRD results show that the crystal structure of PVA is retained in the hydrogel after the addition of CMC,but the crystallinity decreases.The improvement of the mechanical properties of these hydrogels is due to the hydrogen bonding of the hydroxyl in CE,CMC and PVA molecules as well as other interactions between molecular chains,which improve the fusion between molecular chains and enhance the bonding strength among various components.Especially,when the mass ratio of CMC to PVA is 1:5,its tensile modulus of elasticity can reach 39.86 kPa,and the compressive modulus of elasticity can reach to 273.31 kPa.Photoluminescence(PL)results show that the PVA/CMC/CE hydrogel has the ^(5)D_(0)→^(7)F_(2) characteristic emission peak of Eu^(3+) near 635 nm when the excitation wavelength is 394 nm.It displays red fluorescence under ultraviolet light,indicating that the hydrogel has a basis for potential applications in fluorescent probes,anti-counterfeiting and biomarkers.
作者
叶君
叶芳
熊犍
YE Jun;YE Fang;XIONG Jian(State Key Laboratory of Pulp and Paper Engineering,South China University of Technology,Guangzhou 510640,Guangdong,China;School of Food Science and Engineering,South China University of Technology,Guangzhou 510640,Guangdong,China)
出处
《华南理工大学学报（自然科学版）》
EI
CAS
CSCD
北大核心
2021年第9期37-45,共9页
Journal of South China University of Technology(Natural Science Edition)
基金
国家自然科学基金资助项目(22178128,31270617)
华南理工大学制浆造纸工程国家重点实验室资助项目(2016C12)。
关键词
羧甲基纤维素/稀土复合物
羧甲基纤维素
聚乙烯醇
水凝胶
荧光性能
力学性能
carboxymethyl cellulose/rare earth complex
carboxymethyl cellulose
polyvinyl alcohol
hydrogel
fluorescence property
mechanical property
