摘要
柴胡为我国大宗药材之一,其含有的主要活性成分柴胡皂苷具有抗氧化、抗炎、抗癌等药理作用,被广泛应用于中药方剂配伍和中成药生产中。传统柴胡皂苷提取方法存在时间长、效率低、损失大等问题,大大降低了柴胡原药利用率与生产效率。近年来,基于各种新兴技术与新型仪器的高效提取检测方法具有很大的开发和研究价值。综述了中药材柴胡活性成分柴胡皂苷提取纯化工艺及其成分检测手段的研究进展,为柴胡皂苷的开发应用和进一步研究提供理论依据。
Radix bupleuri is one of the bulk medicinal materials in China.The main active component saikosaponin contained in radix bupleuri has the pharmacological effects of anti-oxidation,anti-inflammation and anti-cancer,which is widely used in the compatibility of traditional Chinese medicine prescriptions and the production of Chinese patent medicines.The traditional saikosaponin extraction method has the problems of long time,low efficiency and large loss,which greatly reduces the utilization rate and production efficiency of radix bupleuri.In recent years,efficient extraction and detection methods based on various emerging technologies and new instruments have great development and research value.The research progress of extraction and purification technology and component detection methods of saikosaponin,the active ingredient of radix bupleuri was reviewed,and provides a theoretical basis for the development and application of saikosaponin and further research.
作者
彭依晴
刘爽
康泽鹏
杜晨阳
梁宗锁
PENG Yi-qing;LIU Shuang;KANG Ze-peng;DU Chen-yang;LIANG Zong-suo(College of Life Sciences,Northwest A&F University,Yangling 712100,China;College of Chemistry and Pharmacy,Northwest A&F University,Yangling 712100,China;College of Life Science and Medicine,Zhejiang Sci-Tech University,Hangzhou 310000,China)
出处
《化学试剂》
CAS
北大核心
2021年第12期1677-1682,共6页
Chemical Reagents
基金
陕西省重点研发计划项目(2017TSCL-SF-11-2,2019TSLSF02-02)。
关键词
柴胡
活性成分
柴胡皂苷
提取工艺
检测方法
radix bupleuri
active ingredient
saikosaponin
extraction process
detection method
