摘要
目的应用三维斑点追踪技术(3D-STI)评价甲状腺功能正常的桥本氏甲状腺炎(eHT)患者左心室收缩功能。方法将就诊于湖南中医药大学第一附属医院患者分为健康的对照组(n=40)和诊断为桥本氏甲状腺炎而甲状腺功能正常患者的eHT组(n=43),应用常规超声心动图获得主要参数,包括左心室舒张末内径(LVEDD)、左心室舒张末容积(LVEDV)、左心室射血分数(LVEF)、舒张早期室间隔和左心室侧壁峰值速度平均值(Avg e’)、二尖瓣舒张早晚期血流速度与舒张早期室间隔和左心室侧壁峰值速度平均值之比(E/e’)。应用3D-STI技术获得左心室应变参数,包括左心室整体纵向收缩峰值应变(LVGLS)、左心室整体圆周收缩峰值应变(LVGCS)、左心室整体径向收缩峰值应变(LVGRS)和左心室整体面积收缩峰值应变(LVGAS)。结果与对照组相比,eHT组常规超声参数LVEDD、LVEDV、LVEF、Avg e’、E/e’差异均无统计学意义;eHT组三维应变参数LVGLS小于对照组(P<0.05);与对照组相比,eHT组3D-STI参数LVGCS、LVGRS、LVGAS差异无统计学意义。结论本研究发现即使在甲状腺功能正常的桥本氏甲状腺炎患者中,其左心室心肌动力学仍具有负性改变。
AIM To evaluate the left ventricular systolic function in euthyroid Hashimoto ’s thyroiditis(eHT) patients with normal thyroid functions using three-dimensional spot tracking technology(3 D-STI).METHODS Forty-three patients diagnosed with euthyroid Hashimoto’s thyroiditis were selected as eHT group and forty healthy controls matched by sex and age were selected by three-dimensional spot tracking technology(3 D-STI). The parameters obtained by conventional echocardiography mainly included left atrial diameter(LAD), left atrial volume index(LAVI), left ventricular end-diastolic diameter(LVEDD), left ventricular end-diastolic volume(LVEDV), left ventricular ejection fraction(LVEF), the ratio of the mitral valve late early diastolic blood flow velocity(E/A), early diastolic interventricular septum and left ventricular wall average peak velocity(Avg e’), and mitral valve late early diastolic blood flow velocity and peak early diastolic interventricular septum and left ventricular wall velocity ratio of the average(E/e’). The left ventricular strain parameters obtained by 3 D-STI technology included the overall longitudinal left ventricular systolic peak strain(LVGLS), left ventricular whole circumference(LVGCS), left ventricular systolic peak strain whole radial(LVGRS) and left ventricular systolic peak strain of whole area of systolic peak strain(LVGAS). RESULT S There were no statistically significant differences in the parameters of LAD, LAVI, LVEDD, LVEDV, LVEF, E/A, Avg e ’and E/e’ between eHT group and control group(all P<0.05). The 3 D strain parameter LVGLS in eHT group was smaller than that in control group(P<0.05).There were no significant differences between eHT group and control group in three-dimensional ultrasonic parameters LVGCS, LVGRS and LVGAS. CONCLUSION The findings suggest that the dynamics of left ventricular myocardium remain negatively altered in Hashimoto’s thyroiditis patients with normal thyroid function. Therefore, medication is needed to prevent damage to left ventricular systolic function even in patients with normal thyroid functions.
作者
王琳玲
谢佳佳
余习蛟
王月爱
阳倩
陈晓琼
周琼
WANG Lin-ling;XIE Jia-jia;YU Xi-jiao;WANG Yue-ai;YANG Qian;CHEN Xiao-qiong;ZHOU Qiong(Department Of Ultrasound Imaging,First Hospital,Hunan University of Chinese Medicine,Changsha 410000,Hunan,China;Department of Ultrasound Imaging,Hunan Provincial People’s Hospital,Changsha 410005,Hunan,China)
出处
《心脏杂志》
CAS
2021年第5期523-526,共4页
Chinese Heart Journal
