摘要
目的分析左西孟旦和盐酸多巴酚丁胺在急性心衰中的临床治疗效果。方法对2019年1-12月在该院接受治疗的急性心衰患者56例进行研究,在患者入院时进行编码,1~28号患者纳入对照组,给予盐酸多巴酚丁胺治疗,29~56号患者纳入观察组,给予左西孟旦治疗。评估两组患者治疗前后的心功能指标,对比临床治疗效果。结果观察组患者临床治疗有效率是92.86%(26/28),与对照组的71.43%(20/28)相比更高,差异有统计学意义(χ^(2)=4.383,P<0.05);观察组治疗前的心功能指标LVEF、LVEDV、LVESV水平分别是(38.27±4.16)%、(224.64±77.23)mL、(148.50±58.39)mm,与对照组各项指标值(37.80±5.44)%、(224.81±75.63)mL、(147.70±43.66)mm相比差异无统计学意义(P>0.05),治疗后,观察组患者的LVEF(50.44±6.57)%、LVESV(109.40±11.03)mm水平均较对照组(46.50±6.45)%、(128.68±47.60)mm更优,差异有统计学意义(t=2.264、2.088,P<0.05),在LVEDV指标方面,观察组治疗后(191.57±74.12)mL与对照组(196.10±74.70)mL差异无统计学意义(t=0.228,P>0.05)。结论左西孟旦与盐酸多巴酚丁胺都可治疗急性心衰,但前者治疗有效性更高,对患者的心功能改善效果也更好。
Objective To analyze the clinical therapeutic effect of levosimendan and dobutamine hydrochloride in acute heart failure.Methods A study was conducted on 56 patients with acute heart failure who were treated in the hospital from January to December 2019.The patients were coded when they were admitted to the hospital.Patients 1-28 were included in the control group and given dopphenol hydrochloride,and the patients 29-56 were included in the observation group and given levosimendan treatment.The cardiac function indexes of the two groups were evaluated before and after treatment,and the clinical treatment effects were compared.Results The effective rate of clinical treatment in the observation group was 92.86%(26/28),which was higher than 71.43%(20/28)in the control group,the difference was statistically significant(χ^(2)=4.383,P<0.05);the cardiac function indexes LVEF,LVEDV and LVESV levels of the observation group before treatment were(38.27±4.16)%,(224.64±77.23)mL,(148.50±58.39)mm,respectively,and the index values of the control group were(37.80±5.44)%,(224.81±75.63)mL,(147.70±43.66)mm,the difference was not statistically significant(P>0.05).After treatment,the observation group's LVEF(50.44±6.57)%,LVESV(109.40±11.03)mm level,better than the control group(46.50±6.45)%,(128.68±47.60)mm,the differences were statistically significant(t=2.264,2.088,P<0.05),in terms of LVEDV indicators,the observation group after treatment(191.57±74.12)mL and the control group(196.10±74.70)mL had no statistically significant difference(t=0.228,P>0.05).Conclusion Both levosimendan and dobutamine hydrochloride can treat acute heart failure,but the former is more effective in treatment and has a better effect on improving the patient's heart function.
作者
赵国印
ZHAO Guoyin(Emergency Department,Mudan People's Hospital of Heze,Heze,Shandong Province,274000 China)
出处
《系统医学》
2021年第20期92-94,共3页
Systems Medicine
关键词
左西孟旦
盐酸多巴酚丁胺
急性心衰
心功能指标
Levosimendan
Dobutamine hydrochloride
Acute heart failure
Heart function index
