摘要
目的分析双氯芬酸钠对内镜逆行胰胆管造影术(ERCP)后急性胰腺炎的预防作用。方法选取2018年1月-2020年8月该院收治的84例接受ERCP术治疗的患者为研究对象,随机双盲抽签分为对照组、观察组,各42例。观察组在手术基础上应用双氯芬酸钠,对照组不另外用药,比较两组术后急性胰腺炎及其他并发症发生情况、术后不同时间血清淀粉酶水平。结果观察组术后并发症发生率为2.38%,低于对照组术后并发症发生率19.05%,差异有统计学意义(χ^(2)=4.480,P<0.05)。观察组术后住院时间为(5.53±1.96)d,总住院费用为(1.26±0.52)万元,均少于对照组(7.27±1.62)d、(1.79±0.66)万元,差异有统计学意义(t=4.435、4.088,P<0.05)。两组术后6、24 h血清淀粉酶水平及术后白细胞计数比较,差异无统计学意义(P>0.05)。结论ERCP术后应用双氯芬酸钠塞肛可有效减少术后急性胰腺炎的发生,能缩短患者术后住院时间,减少住院费用。
Objective To analyze the preventive effect of diclofenac sodium on acute pancreatitis after endoscopic retrograde cholangiopancreatography(ERCP).Methods 84 patients treated with ERCP in the hospital from January 2018 to August 2020 were randomly divided into control group and observation group,with 42 cases in each group.The observation group was treated with diclofenac sodium on the basis of operation,and the control group was not treated separately.The incidence of postoperative acute pancreatitis and other complications and the level of serum amylase at different times were compared between the two groups.Results The incidence of postoperative complications in the observation group was 2.38%,which was lower than 19.05%in the control group,and the difference was statistically significant(χ^(2)=4.480,P<0.05).The postoperative hospitalization time of the observation group was(5.53±1.96)d,and the total hospitalization cost was(1.26±0.52)million yuan,which was lower than that of the control group(7.27±1.62)d and(1.79±0.66)million yuan,and the difference was statistically significant(t=4.435,4.088,P<0.05).There was no significant difference in serum amylase level and postoperative leukocyte count between the two groups at 6 and 24 h after operation(P>0.05).Conclusion The application of diclofenac sodium anal plug after ERCP can effectively reduce the incidence of postoperative acute pancreatitis,shorten the postoperative hospital stay and reduce the hospitalization cost.
作者
易金霞
YI Jinxia(Department of Gastroenterology,the Third People's Hospital of Yancheng,Yancheng,Jiangsu Province,224000 China)
出处
《系统医学》
2021年第19期98-100,共3页
Systems Medicine
关键词
双氯芬酸钠
内镜逆行胰胆管造影术
急性胰腺炎
预防
Diclofenac sodium
Endoscopic retrograde cholangiopancreatography
Acute pancreatitis
Prevention
