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糖尿病视网膜病变患者OCT前期检测的临床结果及价值分析

Clinical Results and Value Analysis of Pre-OCT Detection in Patients with Diabetic Retinopathy
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摘要 目的:分析光学相干断层扫描(OCT)前期检测在糖尿病视网膜病变(DR)患者中的诊断价值。方法:将2018年7月~2020年6月本院收治的820例(1640眼)未出现视网膜病变的糖尿病患者作为观察组,同期体检的120名(240眼)健康者分为对照组。均接受OCT检查,分析检测结果及OCT的诊断价值。结果:OCT检查结果显示,观察组下1/4象限、上1/4象限及360˚平均值的视网膜神经纤维层(RNFL)厚度(118.0±12.8)μm、(131.5±14.7)μm、(100.8±9.9)μm均显著低于对照组(128.7±14.3)μm、(137.2±15.8)μm、(105.9±9.3)μm,差异有统计学意义(P<0.05);观察组中270例患者RNFL厚度明显变薄,6个月后复查有175例伴有异常荧光。结论:OCT可通过RNFL厚度可以准确评估DR风险,对人体无创伤,是前期DR的有效诊断方法。 Objective:To analyze the diagnostic value of optical coherence tomography(OCT)in patients with diabetic retinopathy(DR).Methods:A total of 820 diabetic patients(1640 eyes)with no retinopathy admitted to our hospital from July 2018 to June 2020 were divided into a study group,and 120 healthy patients(240 eyes)who underwent physical examination during the same period were divided into a control group.All of them underwent OCT examination,and the test results and the diagnostic value of OCT were analyzed.Results:The results of OCT showed that the lower 1/4 quadrant,the upper 1/4 quadrant and 360˚Mean retinal nerve fiber layer(RNFL)thickness(118.0±12.8)μm,(131.5±14.7)μm,(100.8±9.9)μm was significantly lower than that in the control group(128.7±14.3)μm,(137.2±15.8)μm,(105.9±9.3)μm.The difference was statistically significant(P<0.05);In the observation group,the thickness of RNFL in 270 patients was significantly thinner,and 175 patients were accompanied by abnormal fluorescence after 6 months.Conclusion:OCT can accurately assess the risk of DR through RNFL thickness,which is non-invasive and an effective diagnostic method for early DR.
作者 李贤亮 张志广 叶梦琳 廖晓雪 LI Xian-liang;ZHANG Zhi-guang;YE Meng-lin;LIAO Xiao-xue(Ophthalmology Department,Sanming Hospital of Integrated Traditional Chinese and Western Medicine,Fujian Sanming 365000)
出处 《中国医疗器械信息》 2021年第21期156-157,共2页 China Medical Device Information
关键词 OCT 糖尿病 诊断价值 视网膜病变 OCT diabetes diagnostic value retinopathy
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