摘要
目的:观察清咽解毒茶防治IgA肾病进展的有效性及安全性。方法:采用随机对照法,将符合临床标准的患者随机分为治疗组及对照组,治疗组采用基础治疗及清咽解毒茶治疗,对照组采用基础治疗,验证清咽解毒茶防治IgA肾病毒聚咽喉证的有效性及安全性。通过观察中医证候积分、肾功能、肾小球滤过率、24 h尿蛋白定量、尿常规等评价疗效。结果:与对照组比较,治疗组临床症状减轻(P<0.01),血尿、蛋白尿减少(P<0.05),治疗组总有效率93.5%(29/31),显著高于对照组73.3%(22/30)(P<0.01)。治疗组肾功能有所改善,但与对照组差异无统计学意义。结论:清咽解毒茶联合基础治疗对IgA肾病毒聚咽喉证有较好疗效。
Objective:To observe the efficacy and safety of Qingyan Jiedu Tea in the prevention and treatment of IgA nephropathy.Methods:Patients meeting the clinical standards were randomly divided into the treatment group and the control group.The control group was treated with basic treatment;on which basis,the treatment group was also treated with Qingyan Jiedu Tea.The effectiveness and safety of Qingyan Jiedu Tea were verified in the prevention and treatment of polytoxic throat syndrome of IgA nephropathy.The efficacy was evaluated by observing TCM syndrome integral,renal function,glomerular filtration rate,24-hour urinary protein quantification and urine routine.Results:The clinical symptoms were significantly alleviated(P<0.01),hematuria and proteinuria were reduced in the treatment group compared to those in the control group after the treatment(P<0.05).The total effective rate of the treatment group was 93.5%(29/31),which was significantly higher than 73.3%(22/30)of the control group(P<0.01).The renal function was improved in the treatment group,of which there was no statistical difference between the treatment group and the control group.Conclusion:Qingyan Jiedu Tea combined with basic therapy has a good effect on polytoxic throat syndrome of IgA nephropathy.
作者
邹迪
张守琳
张洪宝
ZOU Di;ZHANG Shoulin;ZHANG Hongbao(Affiliated Hospital of Changchun University of Chinese Medicine,Changchun 130021,China)
出处
《中医药学报》
CAS
2021年第12期72-75,共4页
Acta Chinese Medicine and Pharmacology
基金
国家重点研发计划课题(2019YFC1709903)
吉林省科技厅资助项目(20190201029JC)
吉林省中医药科技项目(2020062)。
关键词
清咽解毒茶
IGA肾病
临床研究
Qingyan Jiedu Tea
IgA nephropathy
Clinical research
