摘要
目的探讨微通道经皮肾镜碎石术治疗肾结石患者的临床效果及对患者炎症因子的影响。方法选取2017年9月至2019年9月湖南航天医院泌尿外科接诊的140例接受微通道经皮肾镜碎石术治疗的肾结石患者作为研究对象,采用计算机随机抽签法将患者分为对照组与观察组,每组各70例。观察组患者接受微通道经皮肾镜碎石术进行治疗,对照组患者接受标准通道经皮肾镜碎石术进行治疗。比较两组患者的各项临床指标、白细胞介素-6(IL-6)和肿瘤坏死因子α(TNF-α)水平以及并发症总发生率。结果观察组患者的手术时间长于对照组,术中出血量少于对照组,卧床时间、住院时间短于对照组,差异有统计学意义(P<0.05);治疗前,两组患者的IL-6、TNF-α水平比较,差异无统计学意义(P>0.05);治疗后,两组患者的IL-6、TNF-α水平高于治疗前,且观察组患者的IL-6、TNF-α水平低于对照组,差异有统计学意义(P<0.05);治疗过程中,观察组患者的并发症总发生率低于对照组,差异有统计学意义(P<0.05)。结论对于肾结石患者来说,采用微通道经皮肾镜碎石术进行疾病治疗,能够取得比传统标准通道手术方法更为优秀的效果,能够有效缩短手术时间,减少患者手术创伤,从而加快患者恢复,同时手术创面的减少也能够降低患者的炎症应激反应,还能够降低患者术后出现并发症的概率,具有推广应用的价值。
Objective To explore the clinical effect of microchannel percutaneous nephrolithotomy in the treatment of patients with kidney stones and its influence on inflammatory factors.Methods A total of 140 patients with kidney stones who were treated with microchannel percutaneous nephrolithotomy and admitted to the Department of Urology,Hunan Aerospace Hospital from September 2017 to September 2019 were selected as the research subjects,and the patients were divided into a control group(n=70)and an observation group(n=70)by computer random drawing method.Patients in the observation group were treated with microchannel percutaneous nephrolithotomy,and patients in the control group were treated with standard-channel percutaneous nephrolithotomy.The clinical indexes,levels of interleukin-6(IL-6)and tumor necrosis factor-α(TNF-α)and the total incidence of complications were compared between the patients of two groups.Results The operation time of the observation group was longer than that in the control group,the intraoperative blood loss was less than that in the control group,and the bed time and hospital stay were shorter than that in the control group,the differences were statistically significant(P<0.05).Before treatment,the IL-6 and TNF-αlevels of patients in the two groups were compared,and the differences were not statistically significant(P>0.05).After treatment,the levels of IL-6 and TNF-αin the two groups were higher than those before treatment,and the levels of IL-6 and TNF-αin the observation group were lower than those in the control group,with statistical significances(P<0.05).During the treatment,the total incidence of complications in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion For patients with kidney stones,the use of microchannel percutaneous nephrolithotomy can obtain better effects than traditional standard channel operation.It can effectively shorten the operation time,reduce the surgical trauma of the patient and accelerate the recovery of the patient.Meanwhile,the reduction of surgical wounds can alleviate the inflammatory stress response of patients,and also reduce the probability of postoperative complications in patients,which has the value of promotion and application.
作者
黄保卿
HUANG Bao-qing(Department of Urology,Hu′nan Aerospace Hospital,Hu′nan Province,Changsha410205,China)
出处
《中国当代医药》
CAS
2021年第34期109-112,共4页
China Modern Medicine
关键词
微通道经皮肾镜碎石术
肾结石
炎症因子
临床疗效
Microchannel percutaneous nephrolithotomy
Kidney stones
Inflammatory factors
Clinical efficacy
