摘要
目的探究益气活血逐瘀方治疗缺血性脑卒中恢复期患者的效果及对其血清神经肽(NPY)、同型半胱氨酸(Hcy)水平和神经功能的影响。方法选取2017年3月—2019年3月于南阳卧龙医院神经内科接受治疗的200例缺血性脑卒中恢复期患者作为此次研究对象,以随机数字表法进行分组,可分为例数均等的对照组、观察组。对照组予以常规西医治疗,观察组在对照组基础上加用益气活血逐瘀方治疗。记录2组治疗前后血清NPY、Hcy水平变化情况,同时评估2组治疗前后神经功能改善情况。结果治疗前,2组血清NPY、Hcy水平基本一致(P>0.05);治疗后,对照组NPY、Hcy水平与治疗前比较差异无统计学意义(P>0.05),而观察组NPY、Hcy水平低于对照组(P<0.05)。治疗前,2组中国脑卒中临床神经功能缺损程度评分量表(CSS)评分基本一致(P>0.05);治疗后,2组CSS评分均已下降,在降幅比较上,观察组大于对照组(P<0.05)。结论在缺血性脑卒中恢复期患者治疗中应用益气活血逐瘀方,可改善患者血清NPY、Hcy水平与神经功能。
Objective To explore the therapeutic effect of invigorating qi and promoting blood circulation for removing blood stasis recipe in treating ischemic stroke in convalescent period and its effect on serum neuropeptide(NPY),homocysteine(Hcy)levels and neurological function.Methods A total of 200 patients with ischemic stroke in the convalescent stage who were treated in the department of neurology of Nanyang Wolong Hospital from March 2017 to March 2019 were selected as the subjects of this study.They were grouped by the random number table method and divided into the control group and the observation group with equal number of cases.The control group conventional western medicine treatment,on the basis of the control group,the observation group received invigorating qi and promoting blood circulation for removing blood stasis recipe.The changes of serum NPY and Hcy levels before and after treatment were recorded in the two groups,and the improvement of neurological function before and after treatment was evaluated.Results Before treatment,serum NPY and Hcy levels of the two groups were basically the same(P>0.05).After treatment,NPY and Hcy levels in the control group were not significantly different from those before treatment(P>0.05),while NPY and Hcy levels in the observation group were lower than those in the control group(P<0.05).Before treatment,the two groups had basically the same score on the scale of clinical neurological impairment(CSS)(P>0.05).After treatment,CSS scores in both groups decreased,and the decrease in the observation group was greater than that in the control group(P<0.05).Conclusion The invigorating qi and promoting blood circulation for removing blood stasis recipe in treating ischemic stroke in convalescent period can improve the levels of serum NPY,Hcy and nerve function.
作者
宋治国
SONG Zhiguo(Department of Neurology,Nanyang Wolong Hospital,Henan Province,Nanyang 473000,China)
出处
《光明中医》
2021年第21期3581-3584,共4页
GUANGMING JOURNAL OF CHINESE MEDICINE
关键词
中风
益气活血逐瘀方
缺血性脑卒中
中医药疗法
apoplexy
invigorating qi and promoting blood circulation for removing blood stasis recipe
ischemic stroke
therapy of TCM
