摘要
目的:探讨心脏康复治疗在慢性心力衰竭(CHF)患者中的应用及对预后的影响。方法:选择CHF患者130例为研究对象,患者被随机分为常规治疗组(常规药物治疗,50例)和心脏康复组(在常规药物治疗基础上联合心脏康复治疗,80例)。心脏康复组根据患者治疗时机进一步分为1周内治疗组(每天治疗5次,每次30min,40例)与1周后治疗组(每天治疗3次,每次30min,40例)。连续治疗3个月,比较各组治疗前后血清N末端脑钠肽前体(NT-proBNP)、C反应蛋白(CRP)水平、简明健康调查表(SF-36)评分及预后情况。结果:治疗3个月后,与常规治疗组比较,心脏康复组血清NT-proBNP[(1521.69±36.15)pg/ml比(325.81±6.33)pg/ml]、CRP[(6.51±1.08)mg/L比(2.41±0.65)mg/L]水平显著降低,SF-36各项评分均显著增加,再住院率(18.00%比6.25%)、死亡率(18.00%比3.75%)均显著降低,P<0.05或<0.01;且与1周后治疗组比较,1周内治疗组血清NT-proBNP[(414.55±8.95)pg/ml比(254.44±2.92)pg/ml]、CRP[(4.15±1.47)mg/L比(2.09±0.61)mg/L]水平均更显著降低,SF-36各项评分均更显著增加,P均=0.001。结论:心脏康复治疗慢性心力衰竭患者效果显著,且其早期进行获益更大,预后更佳。
Objective:To explore application of cardiac rehabilitation(CR)in patients with chronic heart failure(CHF)and its impact on prognosis.Methods:A total of 130 CHF patients were randomly divided into routine treatment group(received routine medication,n=50)and CR group(received CR therapy based on routine medication,n=80).According to therapeutic opportunity,CR group was further divided into therapy within one week group(treated five times per day,30min/time,n=40)and therapy after one week group(treated three times per day,30min/time,n=40).After continuous three-month treatment,serum levels of N terminal pro brain natriuretic peptide(NT-proBNP)and C reactive protein(CRP),36-item short-form heath survey(SF-36)score and prognosis were compared among all groups before and after treatment.Results:Compared with routine treatment group after three-month treatment,there were significant reductions in serum levels of NT-proBNP[(1521.69±36.15)pg/ml vs.(325.81±6.33)pg/ml]and CRP[(6.51±1.08)mg/L vs.(2.41±0.65)mg/L],significant rise in each dimension scores of SF-36,and significant reductions in rehospitalization rate(18.00%vs.6.25%)and mortality(18.00%vs.3.75%)in CR group,P<0.05 or<0.01;compared with therapy after one week group,there were significant reductions in serum levels of NT-proBNP[(414.55±8.95)pg/ml vs.(254.44±2.92)pg/ml]and CRP[(4.15±1.47)mg/L vs.(2.09±0.61)mg/L],and significant rise in each dimension scores of SF-36 in therapy within one week group,P=0.001 all.Conclusion:Cardiac rehabilitation possesses significant therapeutic effect on patients with chronic heart failure,and patients′s benefit are more from early rehabilitation training,and more better for prognosis.
作者
贾鹏
赵运钢
JIA Peng;ZHAO Yun-gang(Department of Emergency,People′s Hospital of Chongqing Banan District,Chongqing,401320,China)
出处
《心血管康复医学杂志》
CAS
2021年第6期661-665,共5页
Chinese Journal of Cardiovascular Rehabilitation Medicine
关键词
心力衰竭
康复
生活质量
Heart failure
Rehabilitation
Quality of life
