摘要
目的探讨左乙拉西坦对癫痫患者认知功能及脑电图改善的影响。方法选取2018年4月至2019年4月本院收治的癫痫患者86例作为研究对象,按照抽签分组法分为对照组与观察组,每组43例。对照组接受卡马西林治疗,观察组接受左乙拉西坦治疗。比较两组临床疗效、认知功能及脑电图改善情况。结果观察组治疗总有效率为95.35%,高于对照组的79.07%,差异有统计学意义(P<0.05)。治疗后,两组FIQ、VIQ、PIQ评分均高于治疗前,且观察组高于对照组,差异有统计学意义(P<0.05)。观察组心电图总改善率为90.70%,高于对照组的72.09%,差异有统计学意义(P<0.05)。结论左乙拉西坦治疗癫痫效果显著,能明显提高患者的认知功能,且有助于改善脑电图,值得临床推广应用。
Objective To investigate the effect of levetiracetam on cognitive function and EEG improvement in epilepsy patients.Methods 86 epilepsy patients from April 2018 to April 2019 were selected as study subjects and they were divided into control and observation groups according to lottery method,with 43 cases in each group.The control group was treated with amazalin and the observation group was treated with levetiracetam.The clinical efficacy,cognitive function and EEG improvement between the two groups were compared.Results The total effective rate of treatment in the observation group was 95.35%,which was higher than 79.07% in the control group,and the difference was statistically significant(P<0.05).After treatment,the FIQ,VIQ and PIQ scores of the two groups were higher than those before treatment,and the observation group was higher than the control group,the difference was statistically significant(P<0.05).The total improvement rate of ECG in the observation group was 90.70%,which was higher than 72.09% in the control group,and the difference was statistically significant(P<0.05).Conclusion The treatment of levetiracetam can significantly improve the cognitive function and helps to improve EEG,it is worthy of clinical application.
作者
刘敬梅
LIU Jingmei(Ward 2,Department of Neurology,Fuxin Second People's Hospital(Fuxin Obstetrics and Gynecology Hospital),Liaoning Province,Fuxin,Liaoning,123000,China)
出处
《当代医学》
2021年第36期75-77,共3页
Contemporary Medicine
关键词
癫痫
左乙拉西坦
认知功能
Epilepsy
Levetiracetam
Cognitive function
