摘要
目的探析肾毒清灌肠黄葵胶囊辅助连续性肾脏替代疗法治疗急性肾衰竭的疗效及对炎症因子水平的影响。方法选取2015年1月至2019年1月本院收治的30例急性肾衰竭患者作为研究对象,按照随机数字表法分为对照组与观察组,每组15例。对照组采用连续性肾脏替代治疗,观察组采用肾毒清灌肠黄葵胶囊辅助疗法治疗。比较两组治疗前后临床各项炎性因子指标、肾功能指标及临床疗效。结果治疗后,观察组IL-1β、IL-6β、TNF-α水平均显著低于对照组,差异有统计学意义(P<0.05)。治疗后,观察组β2-MG、SCr、尿素氮水平均低于对照组,差异有统计学意义(P<0.05)。观察组治疗总有效率为93.33%,明显高于对照组的40.00%,差异有统计学意义(P<0.05)。结论急性肾衰竭患者实施肾毒清灌肠黄葵胶囊辅助连续性肾脏替代疗法可显著降低患者炎性因子水平,保护肾功能,提升临床疗效。
Objective To explore the effect of Shenduqing enema Huangkui capsule assisting continuous renal replacement therapy in the treatment of acute renal failure and its influence on the level of inflammatory factors.Methods 30 patients with acute renal failure admitted to our hospital from January 2015 to January 2019 were selected as the research subjects,and they were divided into control group and observation group according to random number table method,with 15 cases in each group.The control group was treated with continuous renal replacement therapy,and the observation group was treated with Shenduqing enema Huangkui capsule adjuvant therapy.The clinical inflammatory factors and renal function indexes before and after treatment and the clinical efficacy between the two groups were compared.Results After treatment,the levels of IL-1β,IL-6β and TNF-α in the observation group were significantly lower than those in the control group,the difference was statistically significant(P<0.05).After treatment,the levels of β2-MG,SCr and urea nitrogen in the observation group were lower than those in the control group,the difference was statistically significant(P<0.05).The total effective rate of the observation group was 93.33%,which was significantly higher than 40.00% of the control group,the difference was statistically significant(P<0.05).Conclusion The application of Shenduqing enema Huangkui capsule combined with continuous renal replacement therapy in patients with acute renal failure can significantly reduce the level of inflammatory factors,protect renal function and improve clinical efficacy.
作者
于慧超
YU Huichao(Department of Severe Medicine,Shenyang Medical College Affiliated Central Hospital,Shenyang,Liaoning,110024,China)
出处
《当代医学》
2021年第36期80-82,共3页
Contemporary Medicine
关键词
急性肾衰竭
黄葵胶囊
肾毒清灌肠
炎症因子
Acute renal failure
Huangkui capsule
Shenduqing enema
Inflammatory factor
