摘要
目的探讨低碳水化合物饮食干预在促进肥胖型多囊卵巢综合征(PCOS)患者受孕中的作用。方法选取2018年12月至2019年12月大连市妇幼保健院收治的86例肥胖型PCOS患者作为研究对象,采用随机数字表法将其分成研究组和对照组,每组43例。两组患者均予以药物对症治疗和常规护理干预,对照组对饮食进行常规指导,研究组患者则予以低碳水化合物饮食干预。记录两组患者干预前后的体重指数(BMI)、体脂率、空腹胰岛素(FINS)、空腹血糖(FBG)以及睾酮(T)、促卵泡激素(FSH)、黄体生成素(LH)等激素水平的变化情况,随访1年,统计两组干预后1年内的月经周期恢复正常率和受孕成功率。结果干预前,两组患者的BMI、体脂率、FINS、FBG以及各项激素水平比较,差异无统计学意义(P>0.05)。干预后,两组患者的BMI、体脂率、FINS、FBG、T和LH水平均低于干预前,差异有统计学意义(P<0.05);两组干预后的FSH水平与干预前比较,差异无统计学意义(P>0.05)。研究组干预后的BMI、体脂率、FINS、FBG、T和LH水平均低于对照组,差异有统计学意义(P<0.05)。两组干预后的FSH水平比较,差异无统计学意义(P>0.05)。研究组的月经周期恢复正常率和受孕成功率高于对照组,差异有统计学意义(P<0.05)。结论在肥胖型PCOS患者的护理中应用低碳水化合物饮食干预能有效降低体重和体脂,促进糖代谢和生殖内分泌的改善,起到一定的促进受孕的作用。
Objective To explore the effect of low carbohydrate diet intervention in promoting pregnancy of obese polycystic ovary syndrome(PCOS)patients.Methods A total of 86 cases of obese PCOS patients admitted to Dalian Maternal and Child Health Care Hospital from December 2018 to December 2019 were selected as the research objects,and they were randomly divided into the study group and the control group using the random number table method,with 43 cases in each group.Both groups were given symptomatic treatment and routine nursing intervention,while the control group was given routine diet guidance,the study group was given low carbohydrate diet intervention.The changes of body mass index(BMI),body fat rate,fasting insulin(FINS),fasting blood glucose(FBG),testosterone(T),follicle stimulating hormone(FSH),luteinizing hormone(LH)and other hormone levels were recorded before and after intervention in the two groups.The patients were followed up for 1 year,and the menstrual cycle recovery rate and pregnancy success rate of the two groups within 1 year after intervention were counted.Results Before intervention,there were no significant differences in the BMI,body fat rate,FINS,FBG and hormone levels between the two groups(P>0.05).After intervention,BMI,body fat rate,FINS,FBG,T and LH levels of the two groups were lower than those before intervention,the differences were statistically significant(P<0.05).There were no significant differences in FSH levels between the two groups before and after intervention(P>0.05).And the BMI,body fat rate,FINS,FBG,T and LH levels of the study group after intervention were lower than those of the control group,the differences were statistically significant(P<0.05).There was no significant difference in FSH level between the two groups(P>0.05).The menstrual cycle recovery rate and pregnancy success rate of the study group were higher than those of the control group,the differences were statistically significant(P<0.05).Conclusion In the nursing of obese patients with PCOS,the application of low carbohydrate diet intervention can effectively reduce weight and body fat,promote the improvement of glucose metabolism and reproductive endocrine,and play a role in promoting pregnancy.
作者
孙金金
孙林
陶晶
SUN Jin-jin;SUN Lin;TAO Jing(The Fifth Maternity Ward,Dalian Maternal and Child Health Care Hospital,Liaoning Province,Dalian116021,China)
出处
《中国当代医药》
CAS
2021年第35期99-101,105,共4页
China Modern Medicine
基金
辽宁省自然科学基金指导计划项目(2018010800-301)。
关键词
低碳水化合物
饮食干预
肥胖
多囊卵巢综合征
受孕
Low carbohydrate
Dietary intervention
Obesity
Polycystic ovary syndrome
Pregnancy
