摘要
目的探讨中性粒细胞与淋巴细胞比值(neutrophils to lymphocytes ratio, NLR)对不同程度急性脑梗死患者的预测价值。方法采用回顾性方法分析,选取乳源县人民医院内科自2020年6月—2021年6月收治的符合入组条件的91例首诊急性脑梗死患者的临床资料,根据患者神经功能缺损程度(NIHSS评分)对患者进行分组,分析白细胞计数、中性粒细胞绝对值、淋巴细胞绝对值及NLR对不同程度急性脑梗死患者的预测价值。结果除重度脑梗死组中冠心病患者比例显著高于其他2组外,其他基线资料基本一致。重度脑梗死组的NLR、白细胞计数及中性粒细胞绝对值相较于其他2组均显著升高(P<0.05),淋巴细胞绝对值表现出明显的下降趋势,但相较于其他2组尚无统计学意义(P>0.05)。进一步的ROC曲线分析显示NLR相较于其他指标对重度脑梗死具有更好的预测价值。结论 NLR可能作为一种高性价比的指标用于预测急性脑梗死患者严重程度的指标。
Objective To investigate the predictive value of neutrophils to lymphocytes ratio(NLR) in patients with different degrees of acute cerebral infarction. Methods A retrospective analysis was used to select the clinical data of 91 first-diagnosed patients with acute cerebral infarction who were admitted to the Department of Internal Medicine of Ruyuan County People’s Hospital from June 2020 to June 2021. According to the degree of neurological impairment(NIHSS score) divide the patients into groups and analyze the predictive value of white blood cell count, absolute value of neutrophils, absolute value of lymphocytes and NLR in patients with different degrees of acute cerebral infarction. Results Except that the coronary heart disease patients and NIHSS score in the severe cerebral infarction group were significantly higher than the other two groups, other baseline data were basically the same. Compared with the other two groups, the NLR, white blood cell count and absolute value of neutrophils in the severe cerebral infarction group were significantly increased(P<0.05), and the absolute value of lymphocytes showed a significant downward trend, but compared with the other two groups It is not statistically significant(P>0.05). Further ROC curve analysis shows that NLR has a better predictive value for severe cerebral infarction than other indicators. Conclusion NLR may be utilized as a cost-effective indicator to predict the severity of acute cerebral infarction patients.
作者
聂大奥
林桥文
李扬锋
付文
黄建鑫
NIE Daao;LIN Qiaowen;LI Yangfeng;FU Wen;HUANG Jianxin(The Second People’s Hospital of Guangdong Province,Guangzhou 510317,China;Ruyuan County People’s Hospital,Shaoguan 512700,China)
出处
《现代医院》
2021年第12期1953-1955,共3页
Modern Hospitals
基金
广东省医学科研基金(C2021009)。
