摘要
目的观察铍针治疗Ⅲ型前列腺炎对盆腔疼痛和前列腺液中炎症因子的影响。方法将86例Ⅲ型前列腺炎伴盆腔疼痛患者随机分为观察组和对照组,每组43例。对照组予口服双氯芬酸钠缓释片,观察组予铍针疗法。比较治疗前后两组慢性前列腺炎症状指数(NIH-CPSI)总评分及单项评分(盆腔疼痛评分、排尿症状评分、生活质量评分)、国际勃起功能指数评分(IIEF-5)、早泄诊断工具(PEDT)量表评分和胃肠道症状评分(GSRS)的变化,观察治疗前后两组前列腺液中白细胞介素(IL)-6、IL-10、肿瘤坏死因子(TNF)-α和血管细胞黏附因子-1(VCAM-1)水平变化。结果治疗后,两组NIH-CPSI总分、单项评分(疼痛评分、排尿症状评分和生活质量评分)、IIEF-5评分、PEDT评分均较同组治疗前改善(P<0.05),两组前列腺液中IL-6、TNF-α、IL-10和VCAM-1因子水平均较同组治疗前改善(P<0.05)。观察组治疗后NIH-CPSI总分和单项评分(疼痛评分、排尿症状评分)、GSRS评分均优于对照组(P<0.05),观察组治疗后前列腺液中IL-6、TNF-α、IL-10和VCAM-1水平均低于对照组(P<0.05)。结论铍针治疗可改善Ⅲ型前列腺炎伴盆腔疼痛患者的临床症状和性功能,疗效优于口服双氯芬酸钠缓释片,这可能与其降低前列腺液中炎症因子有关。
Objective To observe the effect of stiletto needle therapy on pelvic pain and inflammatory factors in prostatic fluid in typeⅢprostatitis.Method Eighty-six patients with typeⅢprostatitis accompanied by pelvic pain were randomized to an observation group and a control group,with 43 cases in each group.The control group received oral administration of Diclofenac sodium sustained-release tablets and the observation group received stiletto needle therapy.The National Institutes of Health chronic prostatitis symptom index(NIH-CPSI)total scores and item(pelvic pain,urinary voiding symptoms and quality of life)scores,the International index of erectile function 5(IIEF-5)scores,the premature ejaculation diagnostic tool(PEDT)scores and the gastrointestinal symptom rating scale(GSRS)scores were compared between the two groups before and after treatment.Interleukin-6(IL-6),interleukin-10(IL-10),tumor necrosis factor-α(TNF-α)and vascular cell adhesion molecule-1(VCAM-1)in prostatic fluid were measured in the two groups before and after treatment.Result The NIH-CPSI total score and item(pelvic pain,urinary voiding symptoms and quality of life)scores,the IIEF-5 score and the(PEDT score improved in the two groups after treatment compared with before(P<0.05).The levels of IL-6,IL-10,TNF-αand VCAM-1 in prostatic fluid improved in the two groups after treatment compared with before(P<0.05).After treatment,the NIH-CPSI total score and item(pelvic pain,urinary voiding symptoms and quality of life)scores and the GSRS score were better in the observation group than in the control group(P<0.05).After treatment,IL-6,IL-10,TNF-αand VCAM-1 in prostatic fluid were lower in the observation group than in the control group(P<0.05).Conclusion Stiletto needle therapy can relieve the clinical symptoms and improve sexual function in patients with typeⅢprostatitis accompanied by pelvic pain.Its therapeutic effect is superior to that of oral Diclofenac sodium.That may be related to its reducing inflammatory factors in prostatic fluid.
作者
马曜辉
单中杰
郭亮
张楠
MA Yao-hui;SHAN Zhong-jie;GUO Liang;ZHANG Nan(Henan University of Traditional Chinese Medicine People’s Hospital(Zhengzhou People’s Hospital),Zhengzhou 450000,China)
出处
《上海针灸杂志》
2021年第12期1412-1417,共6页
Shanghai Journal of Acupuncture and Moxibustion
基金
国家中医临床研究基地科研专项课题(2019JDZX2092)。
关键词
针刺疗法
铍针
前列腺炎
慢性前列腺炎伴慢性盆腔疼痛综合征
炎症因子
男性
Acupuncture therapy
Stiletto needle
Prostatitis
Chronic prostatitis with chronic pelvic pain syndrome
Inflammatory factor
Male
