摘要
目的:探究富血小板纤维蛋白(PRF)对即刻种植牙周围骨缺损修复的效果。方法:根据即刻种植牙的适应证且通过术前口腔锥形术CT(CBCT)检查均表现为病灶牙有明显的唇侧骨板较薄或骨缺损者纳入研究对象,共纳入74例病人,86颗患牙;将74例病人随机分为观察组和对照组,每组37例病人,观察组共计45颗患牙,采用种植牙同期混入PRF的骨移植材料+口腔修复膜+PRF膜的术式;对照组共计41颗患牙,采用种植牙同期混入骨移植材料+口腔修复膜的术式;术前均测量矢状位患牙唇侧骨板的顶部、中间部、根尖部3个部位厚度;即刻植入种植体,按照上述术式对2组患牙进行处理后严密缝合创面;术后即刻、术后6个月复诊CBCT检查,同时测量矢状位种植体唇侧骨板3个部位厚度及种植体稳定系数(ISQ)值。结果:2组术后即刻和术后6个月的唇侧骨板顶部、中间部和根尖部的测量值均高于拔牙前,差异均有统计学意义(P<0.05);拔牙前、术后即刻唇侧骨板3个部位测量值2组间差异无统计学意义(P>0.05),但术后6个月,观察组3个部分测量值均高于对照组,差异均有统计学意义(P<0.05)。组内比较发现,2组术后6个月ISQ值均高于术后即刻,差异均有统计学意义(P<0.05);但2组间术后即刻、术后6个月ISQ值差异均无统计学意义(P>0.05)。结论:混入PRF的骨移植材料+口腔修复膜+PRF膜较传统的修复方式更能有效的修复唇侧骨缺损,值得临床推广。
Objective:To investigate the effects of platelet-rich fibrin(PRF)in the repair of bone defect around immediate implant teeth.Methods:A total of 74 patients(86 affected teeth)with obvious labial bone plate thinness or bone defect detected by preoperative cone beam CT(CBCT)and conforming to the indications of immediate dental implant were investigated,and divided randomly into the observation group(37 cases,45 teeth)and control group(37 cases,41 teeth).The dental implants in the observation group were treated with the PRF bone graft material,oral repair film and PRF film,and the control group was implanted with bone graft material and oral repair film at the same time.The thickness of the top,middle and apex of labial bone plate in sagittal position in two groups were measured before operation.The NobelReplace Conical Connection was immediately implanted,and the affected teeth in two groups were treated with the above surgical procedures,and the wound surface was tightly sutured.Two groups were examined using CBCT at immediate time after surgery and after 6 months of operation,and the thickness and implant stability quotient(ISQ)of the three parts of the labial bone plate in sagittal implant were measured.Results:The measurement values of the top,middle and apical part of the labial bone plate in two groups at immediate time after surgery and after 6 months of surgery were higher than those before extraction(P<0.05).The differences of the measurement value of three parts of labial bone plate before and at immediate time after tooth extraction were not statistically significant between the two groups(P>0.05),but after 6 months of surgery,the measured values of the three parts in observation group were higher than those in control group(P<0.05).The results of intra-group comparison showed that the ISQ values in the two groups after 6 months of surgery were higher than that at immediate time after surgery(P<0.05).However,there was no statistical significance in the ISQ values at immediate time and after 6 months of surgery between the two groups(P>0.05).Conclusions:Compared with the traditional repair method,the PRF bone graft material,oral repair film and PRF film can more effectively repair the labial bone defect,which is worthy of clinical promotion.
作者
徐济群
胡茂能
黄伟
龚乃胜
张燕
XU Ji-qun;HU Mao-neng;HUANG Wei;GONG Nai-sheng;ZHANG Yan(Department of Oral,The Third Clinical College of Anhui Medical University,Hefei Anhui 230032,China;Department of Radiology,The Third Clinical College of Anhui Medical University,Hefei Anhui 230032,China)
出处
《蚌埠医学院学报》
CAS
2021年第12期1684-1687,共4页
Journal of Bengbu Medical College
基金
安徽省重点研究与开发计划项目(1704f0804041)
安徽省合肥市自主创新政策“借转补”资金项目(J2019Y06)。
