摘要
金铁锁是石竹科植物金铁锁的干燥根,是我国西南地区民间常用草药,含有挥发油类、三萜皂苷类等多种化学成分,具有抑菌、抗炎、镇痛、抗氧化等多种药理活性,同时也具有一定的毒性。本文在广泛检索文献基础上对金铁锁植物的化学成分、药理作用、质量控制、现代临床应用和开发利用研究进几个方面进行综述,为金铁锁资源的合理利用提供参考。
Psammosilene Radix is the dried root of Caryophyllaceae plant Psammosilene tunicoides. It is a commonly used herbal medicine in southwestern China, which contains various chemical components such as volatile oils, triterpenoid saponins and etc. It also has a certain degree of toxicity. This article reviewed several aspects of the research on the chemical compositions, pharmacological effects, quality control, modern clinical application, development and utilization of P.Radix on the basis of extensive literature search, so as to provide reference for the rational use of P.Radix resources.
作者
周祖英
晏婷
郑林
王爱民
李勇军
蒲健
黄勇
Zhou Zuying;Yan Ting;Zheng Lin;Wang Aimin;Li Yongjun;Pu Jian;Huang Yong(State Key Laboratory of Functions and Applications of Medicinal Plants,Guizhou Provincial Key Laboratory of Pharmaceutics,Guizhou Medical University,Guiyang 550004,China;School of Pharmacy,Guizhou Medical University;Engineering Research Center for the Development and Appli-cation of Ethnic Medicine and TCM,Ministry of Education;Guizhou Yi Pharmaceutical Co.Ltd.)
出处
《中国药师》
CAS
2021年第12期2231-2237,共7页
China Pharmacist
基金
国家重点研发计划项目(编号:2018YFC1708100)
国家自然科学基金项目(编号:81960763/U1812403)
贵州省科技计划项目(编号:黔科合平台人才[2019]5407/5660、[2017]5601)
中央引导地方科技专项项目(编号:黔科中引地[2018]4006)
贵阳市科研创新团队项目(编号:筑科合同[2017]30-29号)。
关键词
金铁锁
化学成分
药理作用
质量控制
现代临床应用
开发利用
Psammosilene Radix
Chemical compositions
Pharmacological effects
Quality control
Current clinical application
Development and use
