摘要
背景经尿道双极等离子电切术(PKRP)与经尿道前列腺电切术(TURP)是治疗前列腺增生(BPH)的有效手段,PKPP术对人体生理功能影响小,安全性高。目的比较PKRP与TURP治疗老年高危BPH的临床效果及安全性。方法选取2015年3月-2020年3月我院收治的老年高危BPH患者80例,采取计算机随机数字法将其分为观察组(PKRP组)和对照组(TURP组)各40例。比较两组患者围术期指标、并发症发生率,观察手术前后排尿情况[最大尿流率(Qmax)和残余尿量(PVR)]、生活质量(QOL)、病情严重程度[国际前列腺症状评分(IPSS)]、心理[焦虑自评量表(SAS)、抑郁自评量表(SDS)]变化情况。结果PKRP组患者术中出血量少于TURP组,手术时间、膀胱冲洗时间短于TURP组,血红蛋白(Hb)、钠(Na)下降值均低于TURP组(P﹤0.05);术后6个月,两组患者Qmax较术前升高,PVR较术前减少(P﹤0.05),QOL、IPSS评分及SAS、SDS评分均较术前降低(P﹤0.05),组间上述指标比较差异无统计学意义(P﹥0.05);PKRP组患者并发症发生率低于TURP组(P﹤0.05)。结论PKRP与TURP治疗老年高危BPH疗效明确且相近,均可显著改善排尿困难等症状,减少焦虑抑郁情绪,提高生活质量,但PKPP术中出血量较少,手术时间和膀胱冲洗时间较短,并发症发生率较低,手术安全性更好。
Background Transurethral plasmakinetic resection of prostate(PKRP)and transurethral resection of prostate(TURP)are effective methods for the treatment of benign prostatic hyperplasia(BPH).PKPP has little effect on human physiological function and has high safety.Objective To compare the clinical effects and safety of PKRP and TURP in the treatment of elderly high-risk BPH.Methods Eighty elderly high-risk BPH patients admitted to our hospital from March 2015 to March 2020 were selected and divided into observation group(PKRP group)and control group(TURP group)according to the computer random number method,with 40 cases in each group.The perioperative indicators and incidence rate of complications were compared between the two groups.The urination[maximum urinary flow rate(Qmax),post-voiding residual(PVR)],quality of life(QOL),disease severity[international prostate symptom score(IPSS)]and psychology[self-rating anxiety scale(SAS),self-rating depression scale(SDS)]were observed before and after surgery.Results The intraoperative blood loss in PKRP group was less than that in TURP group,and the operative time and bladder irrigation time were shorter than those in TURP group,and the decreases of hemoglobin(Hb)and sodium(Na)were lower than those in TURP group(P<0.05).At 6 months after surgery,the Qmax in the two groups was higher than that before surgery while the PVR was lower than that before surgery(P<0.05),and the QOL score,IPSS score,SAS score and SDS score were all lower than those before surgery(P<0.05),and there were no statistically significant differences in the above indexes between the groups(P>0.05).The incidence rate of complications in PKRP group was lower than that in TURP group(P<0.05).Conclusion PKRP and TURP both have definite and equivalent efficacy in the treatment of elderly high-risk BPH.They can significantly improve the symptoms of dysuria,reduce anxiety and depression and improve the quality of life.However,PKPP has less intraoperative blood loss,shorter operative time and bladder irrigation time,fewer incidence rates of complications and better surgical safety.
作者
刘玮玮
马成民
范龙龙
Liu Weiwei;Ma Chengmin;Fan Longlong(Department of Urology,The First People’s Hospital of Hefei,Hefei 230031,Anhui Province,China)
出处
《现代科学仪器》
2021年第6期83-87,共5页
Modern Scientific Instruments
关键词
前列腺增生
经尿道双极等离子电切术
经尿道前列腺电切术
国际前列腺症状评分
并发症
Benign prostatic hyperplasia
Transurethral plasmakinetic resection of prostate
Transurethral resection of prostate
International prostate symptom score
Complications
