摘要
目的:探讨腹腔镜保守性手术联合醋酸戈舍瑞林治疗卵巢巧克力囊肿的临床应用效果。方法:选取70例卵巢巧克力囊肿患者为研究对象,随机分为观察组与对照组各35例。对照组给予腹腔镜保守性手术治疗,观察组在对照组手术治疗基础上加以醋酸戈舍瑞林治疗。对两组患者的临床疗效、激素水平、复发率、妊娠率、不良反应发生率等进行评估比较。结果:观察组总有效率为91.43%(32/35),高于对照组患者的71.43%(25/35);差异有统计学意义(P<0.05)。治疗后两组患者的血清卵泡刺激素(FSH)、黄体生成素(LH)、雌二醇(E2)水平均有降低,但组间FSH、LH比较,差异无统计学意义(P>0.05),而观察组E2低于对照组,差异有统计学意义(P<0.05)。患者经过为期12个月的随访观察,观察组复发率低于对照组,妊娠率高于对照组,差异有统计学意义(P<0.05)。治疗期间观察组、对照组不良反应发生率分别为17.14%(6/35)、11.43%(4/35),差异无统计学意义(P>0.05)。结论:腹腔镜保守性手术联合醋酸戈舍瑞林治疗卵巢巧克力囊肿的疗效显著,可改善患者的雌激素水平,降低患者复发率,提高患者的妊娠率,治疗安全性良好。
Objective To study the clinical effect of laparoscopic conservative surgery combined with goserelin acetate in the treatment of ovarian chocolate cyst.Method 70 cases of ovarian chocolate cyst patients were selected and randomly divided into observation group and control group,35 cases in each group.The control group was treated with laparoscopic conservative surgery,and the observation group was treated with goserelin acetate on the basis of the control group.The clinical efficacy,hormone level,recurrence rate,pregnancy rate,incidence of adverse reactions of the two groups were evaluated and compared.Results The total effective rate of the observation group was 91.43%(32/35),which was higher than 71.43%(25/35)of the control group(P<0.05).After treatment,the levels of serum follicle stimulating hormone(FSH),luteinizing hormone(LH)and estradiol(E2)in the two groups were decreased,but there was no significant difference in FSH and LH between the two groups(P>0.05),while E2 in the observation group was lower than that in the control group(P<0.05).After 12 months of follow-up,the recurrence rate of the observation group was lower than that of the control group,and the pregnancy rate was higher than that of the control group(P<0.05).During the treatment,the incidence of adverse reactions in the observation group and the control group were 17.14%(6/35)and 11.43%(4/35)(P>0.05).Conclusion Laparoscopic conservative surgery combined with goserelin acetate in the treatment of ovarian chocolate cyst has significant curative effect,can improve the estrogen level of patients,reduce the recurrence rate of patients,improve the pregnancy rate of patients with good safety.
作者
陆锡洲
LU Xi-zhou(The second People's Hospital of Foshan City,Guangdong Province,Foshan 528000,China)
出处
《吉林医学》
CAS
2021年第12期2903-2906,共4页
Jilin Medical Journal
关键词
卵巢巧克力囊肿
腹腔镜手术
醋酸戈舍瑞林
临床疗效
激素水平
复发率
妊娠率
Ovarian chocolate cyst
Laparoscopic surgery
Goserelin acetate
Clinical efficacy
Hormone level
Recurrence rate
Pregnancy rate
