摘要
目的评价延续护理对糖尿病肾病维持性血液透析(maintenance hemodialysis,MHD)患者生存质量、血糖指标及并发症情况的影响效果。方法由2名研究生检索CNKI、SinoMed、VIP、WanFang Data、PubMed、Embase、Cochrane Library、EBSCO、Web of Science、BMJ、Ovid数据库中延续护理对糖尿病肾病MHD患者生存质量、血糖指标及并发症发生率影响的随机对照试验(RCT),检索时间从建库至2021年4月5日,使用RevMan 5.4.1进行Meta分析。结果纳入文献16篇,共1077例患者。Meta分析显示,延续护理可提高患者生存质量[WMD=12.87,95%CI(2.41,23.33),P=0.02];改善患者血糖指标:空腹血糖(FBG)[WMD=-0.89,95%CI(-0.97,-0.81),P<0.00001],餐后2 h血糖(2 h PG)[WMD=-2.07,95%CI(-2.42,-1.72),P<0.00001],糖化血红蛋白(HbA1C)[WMD=-1.21,95%CI(-1.26,-1.15),P<0.00001];降低患者并发症发生率[OR=0.18,95%CI(0.12,0.29),P<0.00001]。结论与常规护理相比,延续护理能有效提高糖尿病肾病维持性血液透析患者的生存质量,改善血糖,降低并发症发生率。
Objective To investigate the effect of continuous nursing on diabetic nephropathy patients with maintenance hemodialysis.Methods Two graduate students searched randomized controlled trials of the effect of continuous nursing on maintenance hemodialysis patients with diabetic nephropathy in CNKI,CBM,VIP,Wanfang,PubMed,EMBASE,Cochrane Library,EBSCO,Web of Science,BMJ and Ovid databases.RevMan 5.4.1 was used to conduct meta-analysis.Results A total of 19 literatures were included,involving 1077 patients.Meta-analysis showed that continuous care could improve the patients’quality of life[WMD=12.87,95%CI(2.41,23.33),P=0.02]and patients’blood glucose indexes:FBG[WMD=-0.89,95%CI(-0.97,-0.81),P<0.00001],2 h PG[WMD=-2.07,95%CI(-2.42,-1.72),P<0.00001],HbA1C[WMD=-1.21,95%CI(-1.26,-1.15),P<0.00001]and reduce complication rate[OR=0.18,95%CI(0.12,0.29),P<0.00001].Conclusion Compared with routine care,continuous care can improve the quality of life,reduce the blood glucose and complication rate.
作者
陈艺曦
云洁
陈倩
袁雷
吴琪
龚桃林
刘芯言
CHEN Yi-xi(Chengdu University of Chinese Medicine,Chengdu 610072,China)
出处
《牡丹江医学院学报》
2022年第1期76-80,共5页
Journal of Mudanjiang Medical University
关键词
延续护理
糖尿病肾病
维持性血液透析
META分析
循证护理
continuous nursing
diabetic nephropathy
maintenance hemodialysis
Meta-analysis
Evidence-based nursing
